定量感觉检查在糖尿病周围神经病变早期筛查中的灵敏度和特异度研究  

The sensitivity and specificity of quantitative sensory testing in screening diabetic peripheralneuropathy of the early stage

作　　者：谢放[1] 钟历勇[1] 张春芳[1] 范虹[1] 徐剑[1] 李征[1] 

机构地区：[1]首都医科大学附属北京天坛医院内分泌科,100050

出　　处：《中国医师进修杂志》2011年第13期27-30,共4页Chinese Journal of Postgraduates of Medicine

摘　　要：目的 探讨定量感觉检查（QST）在糖尿病周围神经病变早期筛查中的临床意义.方法 分别对100例2型糖尿病患者进行神经传导速度检查和QST,以神经传导速度检查结果阳性为诊断糖尿病周围神经病变的金标准,探讨QST用于早期筛查糖尿病周围神经病变的灵敏度和特异度.结果 100例2型糖尿病患者中.神经传导速度检查结果阳性者41例,阴性者59例;同时QST阳性者74例,阴性者26例.QST用于早期筛查糖尿病周围神经病变的灵敏度为97.56%（40/41）,特异度为42.37%（25/59）.结论 QST在糖尿病周围神经病变的早期筛查中灵敏度较高,但特异度较低,可作为常规肌电图的补充检查.Objective To evaluate the clinical significance of quantitative sensory testing （QST） in screening diabetic peripheral neuropathy of the early stage. Methods One hundred patients with type 2 diabetes mellitus were examined by nerve conduction velocity （NCV） and QST examination. With the NCV positive as the gold criterion for screening diabetic peripheral neuropathy of the early stage, the sensitivity and specificity of QST was further analyzed for diagnosis of the early stage diabetic peripheral neuropathy. Results Among the 100 patients with type 2 diabetes mellitus,there were 41 cases positive and 59 cases negative in NCV examination. On the other hand,there were 74 cases positive,and 26 cases negative in QST. The sensitivity and specificity of QST for the diagnosis of early stage diabetic peripheral neuropathy was 97.56% （40/41） and 42.37% （25/59）. Conclusions In the screening of early stage diabetic peripheral neuropathy,QST shows higher detection sensitivity,but lower specificity than NCV examination. Therefore, QST may be an examination for the supplement of the routine electromyography.

关 键 词：糖尿病神经病变 敏感性与特异性 肌电图描记术 定量感觉检查 

分 类 号：R587.2[医药卫生—内分泌]