2型糖尿病患者胰岛素样生长因子-2与骨密度的关系  

Relationship between Insulin-Like Growth Factor 2(IGF-2) and Bone Mineral Density in Patients with Type2 Diabetes

作　　者：隋春华[1] 陈奕[1] 余娇[1] 赵丽娟[1] 陈鑫[1] 陆颖理[1] 

机构地区：[1]上海交通大学医学院附属第九人民医院内分泌科,上海200011

出　　处：《中国临床医学》2011年第2期196-197,共2页Chinese Journal of Clinical Medicine

摘　　要：目的:研究2型糖尿病患者病程、空腹C肽水平、骨密度与血清胰岛素样生长因子-2(IGF-2)的关系。方法:96例2型糖尿病患者,均测量身高、体质量、骨密度、骨密度以及空腹血清C肽和IGF-2水平。分析糖尿病病程、IGF-2、骨量以及空腹C肽水平之间的关系。结果:随着糖尿病病程延长,IGF-2水平下降;随着骨密度水平下降,IGF-2水平下降;随着空腹C肽水平下降,IGF-2水平下降。结论:IGF-2可能参与了2型糖尿病的进程和骨质疏松的发生。Objective：To study the relationship between the serum level os insulin-like growth factor 2（IGF-2） and bone mineral density（BMD） in patients with type2 diabetes（DM）.Methods：Height,weight,fasting serum C-peptide,IGF-2,and BMD were measure in 96 patients with DM.The associations among the levels of IGF-2,C-peptide and BMD were analyzed.Results：As the years of being DM gets longer,the level of IGF-2 gets lower.BMD was positively related with the lever of IGF-2.When the level of C-peptide decreased,the level of IGF-2 tended to be lower.Conclusions：IGF-2 may contribute to the DM outbreak and the occurrence of osteoporosis.

关 键 词：2型糖尿病 胰岛素样生长因子-2 C肽 骨质疏松 

分 类 号：R587.1[医药卫生—内分泌]