脑外伤后综合征rCBF显像的临床价值  

Clinical Significance of Regional Cerebral Blood Flow Imaging in the Patients with Post Traumatic Syndrome

作　　者：杨世坚[1] 刘春仪[1] 林小红[1] 蒋宁一[2] 卢献平[2] 

机构地区：[1]广东省清远市人民医院核医学科,清远511500 [2]中山医科大学附属孙逸仙纪念医院核医学科,广州510120

出　　处：《现代临床医学生物工程学杂志》1999年第3期168-169,共2页Journal of Modern Clinical Medical Bioengineering

摘　　要：目的:探讨局部脑血流(rCBF)显像对脑外伤后综合症(PTS)的临床价值.方法:对14例正常对照和68例PTS患者同期进行rCBF显像和CT检查,比较二者的诊断效能,探讨PTS的发病机理.结果:(1)PTS的病理生理基础主要是脑实质多发性弥漫性损害,心理因素仅起次要作用.(2)rCBF显像诊断PTS灵敏度(80.9%),明显高于CT(13.2%)(P<0.01).(3)rCBF显像阳性性率在原发脑外伤类型(脑震荡、脑挫裂伤、脑血肿)之间、脑外伤程度(轻、中、重)之间以及病程为3～6月、7～12月、>12月之间无显著性差异(p均>0.05).结论:PTS的主要病理生理基础是脑实质的多发性弥漫性损害,rCBF显像对PS的诊断效能优于CT,rCBF显像阳性率与脑外伤的类型、程度和病程无关.Purpose: To explore the clinical significance of regional cerebral blood flow(rCBF)imaging in the patients with posttraumatic syndrome(PTS).Methods:68 patients with PTS and 14 healthy volunteers were examined with rBCF imaging and CT to compare with their the diagnostic efficiency and explore the mechanism of PTS. Reaults: 1 . The principal pathophysiological basis of PTS was the mulitiple diffuse injury of the brain in which psychological factor only played a minor role. 2. The sensitivity and specificity of rCBF imaging were 80.9% and 84.1% versus13.2% and 28% for CT (p<0.01).3.The positive rate of rCBF imaging was on significant difference in the types of brain injury, the injury scale and the course of PTS is the injury (p> 0 .05 ) . Conclusions : The principal pathophysiologial basis of the multiple diffuse injury of the brain. The rCBF imaging is superior to CT for the dianosis of PTS. The positive rate of rCBF imaging was no significant difference in the types of brain injury, the injury scale ami the course of the injury.

关 键 词：脑外伤后综合症 局部脑血流 放射性核素显像 

分 类 号：R651.15[医药卫生—外科学] R817.41[医药卫生—临床医学]