准确构建个体化膝关节有限元解剖模型的方法  

A method for accurate reconstruction of subject-specific anatomical finite element model of knee joint

作　　者：董跃福[1] 董英海[1] 胡广洪[2] 张华[2] 胡杨[2] 徐卿荣[1] 

机构地区：[1]上海交通大学医学院附属仁济医院骨科,上海200127 [2]上海交通大学塑性成形工程系,上海200030

出　　处：《临床骨科杂志》2011年第2期198-203,共6页Journal of Clinical Orthopaedics

基　　金：国家自然科学基金项目(编号:81071235);上海交通大学"医工(理)交叉研究基金"项目(编号:YG2010MS26)

摘　　要：目的利用多模态影像数据融合和多种建模软件协同应用的方法准确构建膝关节有限元解剖模型,为研究膝关节生物力学行为奠定基础。方法采集正常膝关节CT和MRI影像数据,导入Mimics软件,提取骨、软骨、韧带和半月板,分别构建三维工程化模型。以外部标记物为参照进行模型的配准融合。将膝关节工程化模型导入SC/Tetra和Hypermesh软件,分别进行干涉面删除、网格自定义划分、局部网格优化和体网格划分,构建包含多解剖结构的膝关节有限元模型。结果基于CT和MRI影像数据构建出膝关节骨、软骨、韧带和半月板的三维工程化模型。以三维工程化模型为基础,多种建模软件协同应用构建的有限元模型充分保持了膝关节各结构的解剖学特征。结论利用CT和MRI影像数据融合和多种建模软件协同应用的方法可以构建活体膝关节有限元模型,并保持膝关节各解剖结构的解剖真实性,为准确模拟膝关节生物力学特征提供前提。Objective To accurately reconstruct anatomical finite element model of knee joint through the method of multimodality image data fusion and synergistic applications of three reconstruction software and to further facilitate the investigation of the knee biomechanical behavior.Methods CT and MRI image data of an intact knee joint were imported into Mimics software.Engineered 3D models of bones,cartilages,ligaments and menisci were respectively reconstructed from image data.Then the reconstructed models were registered and fused together based on fixed external landmarks.Following the processes of intersecting surface deletion,user-defined mesh regeneration,optimization and tetrahedral mesh generation in SC/Tetra and Hypermesh software,the knee finite element model,including different anatomical structures,was reconstructed.Results The engineered 3D mode of knee joint composed of bone,cartilage,ligament and meniscus was reconstructed from CT and MRI image data.Based on the 3D model,the knee finite element model reconstructed by three reconstruction software retained the anatomical features of the included structures.Conclusions The method of multimodality image fusion combined with three reconstruction software is applicable to reconstruct the living subject knee finite element model,which retains the anatomical features of knee-related anatomical structures,and offers a useful tool for accurate modeling of the knee biomechanical behavior.

关 键 词：膝关节 三维工程化重建 解剖 网格 有限元模型 

分 类 号：R322.72[医药卫生—人体解剖和组织胚胎学]