2007~2009年南京地区23家医院有严重不良反应报告的中药注射剂应用分析  被引量:8

Application Analysis of Traditional Chinese Medicine Injections with Serious Adverse Drug Reaction Report in 23 Hospitals of Nanjing during 2007-2009

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作  者:储秋萍[1] 冯琳[1] 戴惠珍[2] 陶琳[3] 

机构地区:[1]南京医科大学第一附属医院,南京210029 [2]江苏省医药情报研究所 [3]上海市食品药品监督管理局科技情报研究所

出  处:《中国药师》2011年第5期700-702,共3页China Pharmacist

摘  要:目的:分析南京地区部分有严重不良反应报告的中药注射剂的应用状况和趋势。方法:对南京地区23家入网医院2007~2009年使用有严重不良反应报告的中药注射剂的品种、用药金额和用药频度(DDDs)等信息进行统计分析。结果:有严重不良反应报告的中药注射剂主要为心脑血管类药物,其次是其他类及抗感染类药品。心脑血管类中药注射剂用药金额占中药注射剂总金额平均为40.12%,且逐年上升,年增长率分别为39.74%和14.06%,主要品种用药频度亦呈逐年增长趋势。单品种用药金额和DDDs值位居前列的是血栓通、银杏、参麦、生脉和穿心莲内酯。结论:有严重不良反应报告的中药注射剂为临床治疗用药的重要部分,其用药量逐年增长。安全性再评价势在必行。Objective: To analyze the application status and tendency of the traditional Chinese medicine injections with serious adverse drug reactions in Nanjing. Method: The traditional Chinese medicine injections with serious adverse drug reactions in 23 hospitals of Nanjing during 2007-2009 were analyzed statistically according to the variety, consumption sum and defined daily dose ( DDDs ). Result: Major category of traditional Chinese medicine injections with serious adverse drug reactions was cardiovascular drugs,followed by the other kind of drugs and anti-infective drugs. The consumption sum of the cardiovascular drugs was 40. 12% of total sum and showed year-on-year upward trend with annual growth rate of 39.74% and 14.06% ,respectively. DDDs of the major species also had rising tendency. As to the consumption sum and DDDs, Xueshuantong, Yinxing, Shenmai, Shengmai and andrographolide ranked high by turn. Conclusion: Traditional Chinese medicine injections with serious adverse drug reactions are the important part in clinical treatment and their amount of consumption increases every year, therefore reevaluation of the safety is imperative.

关 键 词:中药注射剂 药物不良反应 用药频度 药物分析 安全性评价 

分 类 号:R283.611[医药卫生—中药学]

 

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