Oxalic acid as a simple and efficient organocatalyst for three-component synthesis ofα-amino nitriles  

作　　者：Seyed Mohammad Vahdat Samad Khaksar Maryam Khavarpour 

机构地区：[1]Chemistry Department,Islamic Azad University,Ayatollah Amoli Branch,P.O.Box 678,Amol,Iran [2]Chemical Engineering Department,Islamic Azad University,Ayatollah Amoli Branch,P.O.Box 678,Amol,Iran

出　　处：《Chinese Chemical Letters》2011年第5期543-546,共4页中国化学快报（英文版）

基　　金：supported by the Islamic Azad University,Ayatollah Amoli Branch

摘　　要：A simple,efficient,and general method has been developed for the synthesis ofα-amino nitriles.Oxalic acid as a BrФnsted acid promotes the addition of TMSCN to various imines（generated in situ）.A simple,efficient,and general method has been developed for the synthesis ofα-amino nitriles.Oxalic acid as a BrФnsted acid promotes the addition of TMSCN to various imines（generated in situ）.

关 键 词：Oxalic acid TMSCN BrФnsted acid α-Amino nitriles 

分 类 号：O643.32[理学—物理化学]