Iron-catalyzed ketonization of 2-aryl-1,1-dibromoalkenes with KOAc:Synthesis of α-acetoxy aryl ketones via a Michael-like addition process  

作　　者：Ming Zhao Chun Xiang Kuang Xue Zhi Cheng Qing Yang 

机构地区：[1]Department of Chemistry, Tongji University, Shanghai 200092, China [2]Department of Biochemistry, School of Life Sciences, Fudan University, Shanghai 200433, China

出　　处：《Chinese Chemical Letters》2011年第5期571-574,共4页中国化学快报（英文版）

基　　金：supported by Natural Science Foundation of China(No,30873153);the Key Projects of Shanghai in Biomedical(No.08431902700);the Scientific Research Foundation of State Education Ministry for the Returned Overseas Chinese Scholars

摘　　要：A novel and convenient iron-catalyzed ketonization of 2-aryl-1,1-dibromoalkenes with KOAc has been achieved.A series ofα-acetoxy aryl ketones were prepared with moderate yields via 2-carbon position functionalization of 2-aryl-1,1-dibromoalkenes.A novel and convenient iron-catalyzed ketonization of 2-aryl-1,1-dibromoalkenes with KOAc has been achieved.A series ofα-acetoxy aryl ketones were prepared with moderate yields via 2-carbon position functionalization of 2-aryl-1,1-dibromoalkenes.

关 键 词：Iron catalyst KETONIZATION Dibromoalkene α-Acetoxy ketone Potassium acetate 

分 类 号：O623.626[理学—有机化学] TQ225.241[理学—化学]