多切面联合超声筛查中晚孕胎儿心脏病的探讨  

Multi-views Conjoined Screening for Fetal Heart Disease in the Second and Third Trimester Pregnancy by Prenatal Ultrasonography

作　　者：陈书文[1] 贡雪灏[1] 梁新[1] 熊华花[1] 张琪[1] 李泉水[1] 

机构地区：[1]深圳市第二人民医院超声科,广东省深圳市518035

出　　处：《中国超声医学杂志》2011年第4期357-359,共3页Chinese Journal of Ultrasound in Medicine

基　　金：深圳市医学重点专科课题资助项目(No.2005C06)

摘　　要：目的探讨多切面联合超声在中晚孕胎儿心脏病筛查中的应用价值。方法应用彩超筛查孕18～36周胎儿共16500例。并通过尸体解剖证实和产后超声随访对照,对四腔心观(FCV)、四腔心十三血管-气管观(FCV+3VT)及多切面联合3种方法的诊断价值进行分析。结果共检出先天性心脏病胎儿共96例。多切面联合法的Youden指数(0.904 5)优于FCV法(0.511 7)和FCV+3VT法(0.797 2),P<0.05。3种方法中以多切面联合法的Youden指数及灵敏度最高,漏诊率最低。结论多切面联合扫查的灵敏度最高,漏诊率最低,可作为产前超声筛查中晚期妊娠胎儿心脏的适宜方法 。Objective To investigate multi-views conjoined screening （MVCS） for fetal heart disease in the second and third trimester pregnancy by prenatal ultrasound, Methods The/our-chamber view （FCV） alone, FCV with three vessels and trachea view FCV＋3VT, MVCS of 16500 consecutive fetuses aged from 18 to 36 week were examined to screen for fetal cardiac malformations with color Doppler. Suspected fetal cardiac disease was confirmed by postmortem or postnatal eehocardiography and/or surgery. Then, the sensitivities of screening tests were compared among the three methods. Results 96 fetuses was identified fetal heart disease. The Youden indexes of MVCS （0. 9045）were more than FCV（0. 5117） and FCV＋3VT（0. 7972）（P〈0.05）, Compared with FCV and FCV＋3VT, MVCS was with the most sensitive and lowest missed diagnosis. Conchmions MVCS is a good method to diagnose fetal heart disease in the second and third trimester pregnancy with the most sensitive and lowest missed diagnosis.

关 键 词：产前 胎儿 心脏缺损 超声检查 

分 类 号：R445.1[医药卫生—影像医学与核医学] R714.5[医药卫生—诊断学]