蒙特卡罗方法计算外照射所致红骨髓剂量方法的研究  

Monte Carlo simulation methods of determining red bone marrow dose from external radiation

作　　者：高佚名[1] 刘海宽[1] 顾乃谷[1] 吴锦海[1] 黄卫琴[1] 王凤仙[1] 王力[1] 苏旭[2] 

机构地区：[1]复旦大学放射医学研究所,上海200032 [2]中国疾病预防控制中心辐射防护与核安全医学所

出　　处：《中华放射医学与防护杂志》2011年第2期225-228,235,共5页Chinese Journal of Radiological Medicine and Protection

摘　　要：目的对现有的红骨髓剂量模拟计算方法进行比较和分析，为确定更为合理的计算方法提供依据。方法借助MCNPX蒙特卡罗模拟软件，模拟了能量20keV～10MeV的叮光子源，对Rensselaer理工学院（RPI）体素人体模型进行前后（AP）全身均匀照射，分别采用直接能量沉积法、剂量响应函数法（I）RF）、King-Spiers因子法和质能吸收系数法（MEAC），进行红骨髓剂量的模拟计算。结果在入射1光子能量低于100keV时，直接能量沉积法的结果最大，而质能吸收系数法和King-Spiers因子法的结果更为合理；在入射1光子能量高于150keV时，King-Spiers困子法给出的结果要略高于其他方法的结果，但其能够反映出红骨髓对1光子能量更强的吸收能力．．结论综合比较低能区和高能区不同方法给出的结果后．发现King-Spiers因子法是最合理的估算红骨髓剂量的方法。Objective To provide evidence for a more reasonable method of determining red hone marrow dose by analyzing and comparing existing simulation methods. Methods By utilizing Monte Carlo simulation software MCNPX, the absorbed doses of red bone marrow of Rensselaer Polytechnic Institute （RPI） adult female voxel phantom were calculated through 4 different methods： direct energy deposition, dose response funetion （DRF）, King-Spiers factor method and mass-energy absorption coefficient （MEAC）. The radiation sources were defined as infinite plate sources with the energy ranging from 20 keV to 10 MeV, and 23 sources with different energies were simulated in total. The source was placed right next to the front of the RPI model to achieve a homogeneous anteroposterior radiation scenario. The results of dift^rent simulated photon energy sources through different methods were compared. Results When the photon energy was lower than 100 keV, the direct energy deposition method gave the highest result while the MEAC and King-Spiers factor methods showed more reasonable results. When the photon energy was higher than 150 keV taking into account of the higher absorption ability of red bone marrow at higher photon energy, the result of the King-Spiers factor method was larger than those of other methods. Conclusions The King-Spiers factor method might be the most reasonable method to estimate the red bone marrow dose from external radiation.

关 键 词：蒙特卡罗方法 红骨髓 剂量 人体模型模拟计算 

分 类 号：R687.3[医药卫生—骨科学]