中药血清药理学研究进展  

Advances of Serum Pharmacology of Chinese Medicine

作　　者：黄臣虎[1] 陆茵[1,2] 高骁君[1] 孙志广[1,3] 严令耕[1] 

机构地区：[1]南京中医药大学药学院,南京210029 [2]江苏省方剂重点研究实验室,南京210046 [3]江苏省中医院,南京210029

出　　处：《中国实验方剂学杂志》2011年第10期266-271,共6页Chinese Journal of Experimental Traditional Medical Formulae

基　　金：国家自然科学基金项目(30772766);江苏省自然科学基金项目(BK2007239)

摘　　要：运用中药血清药理学方法研究中药复方的药效、物质基础及作用机制。通过对中药血清药理方法学中对实验动物、给药剂量和给药方案、采血方案、血清灭活与保存、血清添加量和对照组的设立等的确立,建立最佳的实验方案进行研究。文献检索研究表明,中药复方对神经系统有调节作用,能保护心肌细胞,促进血管内皮细胞增殖,预防哮喘,增强免疫,抗菌抗炎抗病毒,抗纤维化并能延缓糖尿病肾病的发展。中药血清药理学在神经、心血管、呼吸、免疫、消化、生殖、泌尿、骨骼系统以及在抗菌、抗炎、抗肿瘤、抗病毒等方面都有很好的应用,为中药复方药理作用的研究提供了良好的方法。Use the methods of serum pharmacology of Chinese medicine study the potency,material base,action mechanism of the compound traditional Chinese medicine.Chose the best experimental scheme by the chosen of animals,administration dosage,dosage regimen,blood sampling regime,control group establishment,inactivation,storage and addition quantity of serum.Compound traditional Chinese medicine can regulate nervous system,protect myocardial cells,promote the proliferation of vascular endothelial cells,prevent asthma,enhance immune,antibacterial,anti-inflammatory,antivirus,anti-fibrosis and delay the development of diabetic nephropathy.Serum pharmacology of Chinese medicine have good application in nervous system,cardiovascular system,respiratory system,immune system,digestive system,reproductive system,urinary system,skeletal system,anti-inflammatory,antivirus and anti-fibrosis etc,which can provide a good method for the compound traditional Chinese medicine research.

关 键 词：中药复方 血清 体外实验 

分 类 号：R285[医药卫生—中药学]