人手皮肤环层小体分布的形态学研究  

The Morphological Study on the Pacinian Corpuscles of the Human Hand

作　　者：王鲁建[1] 刘冰阳[2] 柏树令[1] 

机构地区：[1]中国医科大学基础医学院解剖教研室,沈阳110001 [2]中国医科大学第93期临床医学7年制,沈阳110001

出　　处：《中国医科大学学报》2011年第5期385-386,393,共3页Journal of China Medical University

基　　金：国家自然科学基金资助项目(30772215)

摘　　要：目的研究S-100蛋白和髓鞘碱性蛋白(MBP)在人手指皮肤环层小体上的表达情况。方法采用SP免疫组化方法检测S-100蛋白和MBP在人手指皮肤环层小体上的表达。结果真皮乳头嵴存在于表皮嵴下,与指纹并行排列。环层小体广泛分布在真皮网织层和皮下组织层。皮神经和感觉小体分布在血管和汗腺附近。结论 S-100蛋白和MBP免疫过氧化物酶染色标记施万细胞具有特异性。掌指关节区、鱼际区的环层小体平均数量偏高。Objective To study the expression of S-100 protein and MBP protein in sensory nerve of the human finger＇s skin.Methods The streptavidin-peroxidase immunohistochemical method was used for the study.Results Dermal papilla ridges were below epidermal ridges.Both of them located in the skin side by side.Pacinian corpuscles located in the reticular layer of dermis and the hypodermis.Cutaneous nerves and sensory corpuscles were found in the blood vessels and the sweat glands nearby.Conclusion It is an effect method with S-100 protien and MBP to label the Schwann cell in the nerve fibers.The concentration of the pacinian corpusles in the area of thenar and metacarpophalangeal articulationis was higher.

关 键 词：S-100蛋白 MBP 环层小体 SP免疫组化方法 人皮肤 

分 类 号：R322[医药卫生—人体解剖和组织胚胎学]