间接电还原法合成氟哌酸中间体氟氯苯胺的研究  

Synthesis of 3Cl4F Aniline for Norfloxacin Intermediate Product by Indirect Electroreduction Method

作　　者：顾家山[1] 褚道葆[1] 周幸福[1] 胡继萍[1] 

机构地区：[1]安徽师范大学有机化学研究所

出　　处：《精细化工》1999年第4期31-34,共4页Fine Chemicals

基　　金：安徽省教委自然科学基金

摘　　要：采用电化学还原路线，在离子膜电解槽中，以Ｔｉ／ＴｉＯ２电极作阴极、ＤＳＡ作阳极，经阴极间接电催化还原３氯４氟硝基苯为氟氯苯胺。最佳电解条件为：电流密度７～９Ａ／ｄｍ２，电解液Ｈ２ＳＯ４浓度０．５ｍｏｌ／Ｌ，电解温度５５～６５℃。电流效率８９．５％，电解收率９２．８％，产品纯度９９．６％。Electrosynthesis of 3Cl4F aniline was investigated by indirect electroreduction of 3Cl4F nitrobenzene on Ti/TiO2 electrodes.An optimum electrolytic condition is given in this paper.The optimum current density is found to be 79 Adm-2.The concentration of H2SO4 is 0.5 mol/L,and 5565 is the optimum temperature.The result shows that current efficiency is 89.5%,electrolytic yield is 92.8%,product purity is 99.6%.

关 键 词：氟氯苯胺 氟哌酸 间接电还原 中间体 抗菌素 

分 类 号：TQ246.34[化学工程—有机化工] TQ465