髁突与生长板软骨发育早期组织学特征的比较研究  

Comparison of Growth Characteristics Between Mandibular Condyle Cartilage and Growth Plate Cartilage

作　　者：熊红珍[1] 赵华[1] 王小娟[1] 包丽娜[1] 万贤凤[1] 李松[2] 

机构地区：[1]广东省口腔医院.南方医科大学附属口腔医院番禺分院,广东广州511400 [2]昆明医学院

出　　处：《广东牙病防治》2011年第4期186-189,共4页Journal of Dental Prevention and Treatment

摘　　要：目的探讨髁突软骨与生长板软骨发育早期组织学特征上的异同,进一步了解髁突软骨的发育过程和生长特点,为临床上功能矫形的治疗提供理论依据。方法选用胚胎SD大鼠的髁突软骨与生长板软骨作为研究对象,建立发育早期的动物模型,对两种软骨进行组织切片染色观察,比较它们组织学特征上的异同。结果胎龄14~19 d,髁突软骨与生长板软骨的组织结构大体相似,但存在一定的差异。两种软骨分层不同,细胞形态不同,生长板增殖层和前肥大层软骨细胞更为扁平;细胞排列不同,生长板软骨细胞平行于长骨呈柱状排列,髁突软骨细胞分层排列,无细胞柱;另外,生长板软骨中肥大软骨细胞的出现较髁突软骨早。结论发育早期,髁突软骨与生长板软骨组织结构大体相似,但在软骨细胞分层、形态及排列方式方面存在一定差异。Objective The purpose of this study is to investigate the differences in growth characteristics between condyle cartilage and growth plate during the early stage of development,in order to further recognize the development process and growth characteristics of mandibular condyle cartilage.Methods Condyle cartilage and growth plate were gained from Sprague Dawley rat fetuses respectively on embryonic day 14（E14 d）,E15 d,E16 d,E17 d,E18 d and E19 d.Made anteroposterior axes serial sections.Observe their structure in the way of HE staining.Results During E14 d-E19 d,condyle cartilage and growth plate cartilage had similar structures.But there were some differences between them.One was their layers,the other was the shapes and cell alignment.Proliferative chondrocytes and prehypertrophic chondrocytes of growth plate cartilage were flatter than condyle cartilage.Chondrocytes of growth plate cartilage aligned with lone axis,became many cell columns.In contrast,chondrocytes of condyle cartilage arranged in layers.In growth plate,the time of hypertrophic chondrocytes,presence is earlier than in condyle cartilage.Conclusion In early development,condyle cartilage and growth plate cartilage had similar structures,but there were some differences in chondrocytes layer,shapes and cell alignment.

关 键 词：髁突软骨 生长板软骨 发育 

分 类 号：R323[医药卫生—人体解剖和组织胚胎学]