波强度对川崎病患儿心功能变化的评价  

Evaluation of the left ventricular function of patients with Kawasaki disease using wave intensity

作　　者：张海平[1] 寇红菊[1] 姜淑英[1] 潘赛达[1] 刘咏芳[1] 

机构地区：[1]温州医学院附属第二医院超声科,浙江温州325027

出　　处：《医学影像学杂志》2011年第3期343-346,共4页Journal of Medical Imaging

摘　　要：目的:应用波强度(wave intensity,WI)评价川崎病(kawasaki disease,KD)患儿左室整体收缩和舒张功能变化。方法:本院确诊KD急性期患儿68例,随访至患儿进入恢复期作为病例组,另选无心血管并发症儿童40例作为对照组,对受检者左侧颈总动脉行WI检测,获得WI参数:校正后第一峰值(1ndW1),校正前第一峰值(Wd1),校正后第二峰值(2ndW2),校正前第二峰值(Wd2);颈总动脉僵硬度参数。Simpson法测量受检者左室整体射血分数(EF)和二尖瓣口血流频谱,获得E/A值,两期受检者及两组受检者参数进行对比。结果:与对照组及恢复期患儿比较,急性期患儿左侧颈总动脉僵硬度参数、EF值、E/A值无统计学差异(P>0.05);,急性期1stW1及Wd1与对照组及恢复期患儿比较无统计学差异(P>0.05),而2ndW2及Wd2较对照组及恢复期患儿明显减低,差异有统计学意义(P<0.05),恢复期患儿与对照组各参数比较未见明显差异(P>0.05)。结论:急性期川崎病患儿左室舒张功能会受损,WI技术可以经由颈总动脉无创早期评价KD患儿左心功能变化,并且比颈动脉僵硬度及常规心功能测量等参数更敏感。Objective：To evaluate left ventricular systolic and diastolic function of patients with Kawasaki disease（KD） using wave intensity（WI）.Methods：Sixty-eight patients with KD in acute stage and forty normal ones in the same age range were enrolled in this study.The following WI parameters of patients with KD in acute and recovery stage and in comparative subjects were obtained respectively： the corrected first peak（1 ndW1）,the uncorrected first peak（Wd1）,the corrected second peak（2 ndW2）,the uncorrected second peak（Wd2） and elasticity parameters.Left ventricular ejection fraction（EF） was measured using double plane Simpson method and the value of early diastolic peak velocity E,late diastolic peak velocity A and the ratio of E/A were measured respectively.All the parameters of these two groups and two stages were compared.Results：There were no significant differences of elasticity parameters,EF,E/A,1 ndW1 and Wd1 between the comparative subjects,the KD subjects in recovery stage and the KD subjects in acute stage（P0.05）.But compared with the parameters of the comparative subjects and the KD subjects in recovery stage,2 ndW2 and Wd2 of the acute stage were significantly lower（P0.05）.There were no significant differences between normal ones and recovery stages in patients with KD.Conclusion：KD disease can detect diastolic function of patients with KD.No changes of elasticity parameters,EF and E/A between the two groups happens.The diastolic function is significantly lower in acute stage compared with that of the comparative subjects,which suggests that WI technique can reflect the change of the diastolic function early and noninvasively,and more sensitively compared with elasticity parameters,EF and E/A.

关 键 词：川崎病 心功能 波强度 超声心动描记术 

分 类 号：R541[医药卫生—心血管疾病]