南宁市成人散发性腹泻病例中札幌病毒感染研究  

Sapovirus infection among sporadic adult cases with acute gastroenteritis in Nanning City

作　　者：谭冬梅[1] 刘巍[1] 邓丽丽[1] 唐振柱[1] 谢镇国[1] 黄兆勇[1] 方志锋[1] 杨哲[1] 董柏青[1] 

机构地区：[1]广西壮族自治区疾病预防控制中心,南宁530028

出　　处：《中国人兽共患病学报》2011年第4期294-296,306,共4页Chinese Journal of Zoonoses

基　　金：广西壮族自治区科学技术厅项目(桂科攻9732027;桂科攻0592007-4;08-05-01D);广西壮族自治区卫生厅科研课题(合同号:Z2008214)

摘　　要：目的研究广西南宁市成人散发性腹泻病例中札幌病毒(Sapovirus,SV)的感染状况和流行特征。方法对2007年1月至2008年12月南宁市某医院门诊412例成人腹泻病例的流行病学资料进行分析;并采集粪便标本,应用荧光定量逆转录-聚合酶链反应检测SV。结果在检测的412份粪便标本中,19份阳性,检出率为4.61%(19/412)。病例全部集中在冬春季,年龄范围17-65岁。SV阳性检出率无年龄组和性别差异。结论本研究首次证实SV是南宁市成人散发性腹泻的病原体之一,提示在感染性腹泻病例诊断中要加以考虑SV感染。The study was aimed to describe the prevalence and epidemiology of sapovirus（SV） infection among sporadic adult cases with acute gastroenteritis in Nanning City of Guangxi.The epidemiological data of diarrheic patients who presented to outpatient clinics of a hospital in Nanning City buring January 2007 and December 2008 were analyzed.A total of 412 fecal samples were collected from these patients and tested for the presence of SV RNA using the real-time reverse transcription-polymerase chain reaction.Of the 412 samples assayed,19（4.61%） were positive for SV.The peak of SV infection occurred during cold seasons.The age of SV-infected cases ranged from 17 to 65 years.No significant difference in detection rate was observed among patients belonging to different ages and genders.This study is the first report that confirms SV is one of the enteropathogens responsible for sporadic acute gastroenteritis among adults in Nanning City,suggesting importance should be attached to the role of SV infection in diarrheal diseases.

关 键 词：札幌病毒 散发 腹泻 荧光定量逆转录-聚合酶链反应 

分 类 号：R512.99[医药卫生—内科学]