双水平气道正压通气对慢性阻塞性肺疾病合并阻塞性睡眠呼吸暂停综合征的影响研究  

The Observation in Patients with Overlap Syndrome Treated by Biphasic Positive Airway Pressure

作　　者：梁荣章[1] 吴永泉[1] 

机构地区：[1]福建医科大学附属龙岩市第一医院呼吸内科,福建省龙岩市364000

出　　处：《实用心脑肺血管病杂志》2011年第6期908-909,共2页Practical Journal of Cardiac Cerebral Pneumal and Vascular Disease

摘　　要：目的探讨双水平气道正压通气(BiPAP)对慢性阻塞性肺疾病(COPD)合并阻塞性睡眠呼吸暂停综合征的治疗效果。方法选取60例住院COPD合并阻塞性睡眠呼吸暂停综合征患者,BiPAP治疗前和治疗后行全夜多导睡眠图(PSG)监测,并对治疗前后的监测结果进行分析。结果治疗后呼吸暂停低通气指数(AHI)由41.0±16降至10.0±3.0,平均呼吸暂停时间下降了13s,而最长呼吸暂停时间下降了56s。最低血氧饱和度(SaO2)由(58.2±6.0)%升至(90.5±6.7)%,睡眠效率改善。结论 BIPAP治疗COPD合并阻塞性睡眠呼吸暂停综合征效果确切。Objective To study the effect with Biphasie positive airway pressure（BIPAP）in patients with overlap syndrome.Methods 60 patients of COPD accompany with OSAS were treated by BIPAP,and were measured by polysomnography（PSC）during all-night sleep,analyzed the results before and after treatment.Results After treatment,the average apnea index（AHI） showed a decrease from 41±16 to 10.0±3.0,the average apnea time decreased by 13sec,the 1ongest apnea time decreased by 56sec,the lowest SaO2 increased from（58.2±6.0）% to（90.5±6.7）%.The sleep effect（SE） was increased.Conclusion The ventilation with BIPAP in patients with owerlap syndrome was efficacious.

关 键 词：慢性阻塞性肺疾病 阻塞性睡眠呼吸暂停综合征 疗效 

分 类 号：R563.3[医药卫生—呼吸系统]