对比三维多回波T2~*血管成像与三维时间飞跃法MR血管成像诊断大脑半球梗死患者颅内大血管病变  

Comparison on cerebral infarction with three-dimensional T2~*-weighted angiography and three-dimensional time of flight MR angiography in diagnosis of arterial stenosis or obstruction in patients with unilateral cerebral infarction

作　　者：凌雪英[1] 赵莲萍[1] 刘斯润[1] 黄力[1] 黄立安[2] 徐安定[2] 

机构地区：[1]暨南大学附属第一医院医学影像中心,广东广州510630 [2]暨南大学附属第一医院神经内科,广东广州510630

出　　处：《中国医学影像技术》2011年第5期901-904,共4页Chinese Journal of Medical Imaging Technology

基　　金：广东省自然科学基金([2008]4号8151063201000005)

摘　　要：目的探讨三维多回波T2*血管成像(3D SWAN)诊断大脑半球梗死患者颅内大血管病变的价值。方法对63例单侧脑梗死患者(起病时间为3 h^8天)行常规MR、DWI、3D SWAN及三维时间飞跃法MR血管成像(3D TOFMRA)检查,分析3D SWAN检测的颅内大动脉(包括大脑中动脉和颈内动脉颅内段)异常低信号,与3D TOF MRA显示的异常(中断、闭塞、狭窄)进行比较,判断两种方法对显示动脉异常的一致性,并计算Kappa值。结果 3D TOF MRA共显示28条大脑中动脉、9条颈内动脉中断、闭塞或狭窄,而3D SWAN则显示其中30条动脉出现异常低信号,3D SWAN与3D TOF MRA对显示大脑中动脉和颈内动脉颅内段的异常具有很好的一致性(Kappa值为0.867,P<0.05)。结论 3D SWAN对诊断脑梗死患者大脑中动脉和颈内动脉颅内段异常有较高价值,分析3D SWAN动脉内异常低信号的特点有助于进一步判断3D TOF MRA显示的动脉中断、闭塞、狭窄的原因。Objective To observe the value of three-dimensional T2＊-weighted angiography（3D SWAN） in diagnosis of arterial stenosis or arterial obstruction in cerebral infarction.Methods Totally 63 patients with unilateral cerebral infarction were recruited and underwent conventional MR,three-dimensional time of flight angiography（3D TOF MRA）,DWI and 3D SWAN within 3 h—8 d of symptom onset.The susceptibility hypointensity sign in middle cerebral arteries and internal carotid arteries on 3D SWAN was analyzed and was compared to the abnormalities of corresponding arteries of 3D TOF MRA including stenosis,occlusion and interruption,and the Kappa value was calculated.Results Twenty-eight middle cerebral arteries and 9 internal carotid arteries were demonstrated stenosis,occlusion or interruption on 3D TOF MRA.The susceptibility hypointensity sign was showed in 30 of corresponding arteries on 3D SWAN.There was consistency between susceptibility hypointensity in arteries on 3D SWAN and the stenosis,occlusion or interruption in corresponding arteries on 3D TOF MRA（Kappa value=0.867,P〈0.05）.Conclusion It is valuable for diagnosing the abnormalities of middle cerebral arteries and internal carotid arteries with 3D SWAN.Investigating the characteristics of susceptibility hypointensity sign of 3D SWAN is helpful for showing the etiology of stenosis,occlusion or interruption of cerebral arteries on 3D TOF MRA.

关 键 词：脑梗死 磁共振成像 脑动脉 

分 类 号：R445.2[医药卫生—影像医学与核医学] R743.33[医药卫生—诊断学]