超声斑点追踪显像评价左心室心肌致密化不全患者心肌功能  

Assessment of left ventricular function with speckle tracking imaging in patients with left ventricular noncompaction

作　　者：陆叶[1] 吕秀章[1] 马宁[2] 江勇[1] 徐楠[1] 朱振辉[1] 张红菊[1] 

机构地区：[1]北京协和医学院中国医学科学院阜外心血管病医院超声科,北京100037 [2]北京协和医学院中国医学科学院放射科,北京100037

出　　处：《中国医学影像技术》2011年第5期948-952,共5页Chinese Journal of Medical Imaging Technology

摘　　要：目的应用超声斑点追踪显像技术(STI)定量评价左心室心肌致密化不全(LVNC)患者左心室心肌纵向收缩功能,并探讨其在LVNC诊断中的价值。方法 LVNC患者21例,分为两组:LVNC-1组(n=10):LVEF≥50%;LVNC-2组(n=11):LVEF<50%。以21名年龄性别相匹配的健康志愿者作为正常对照组。采集左心室心尖长轴动态图像,利用STI获取各节段心肌纵向应变(LS)曲线及收缩期峰值应变。结果 LVNC-2组左心室各水平LS均较正常对照组明显减低(P均<0.05),LVEF、E’、E/E’与正常对照组比较差异有统计学意义(P均<0.05)。LVNC-1组LS均较正常对照组减低(P均<0.05),但其E’、E/E’与正常对照组无明显差异。取左心室心尖段LS均值-20.71%为界值,诊断LVNC患者左心室纵向收缩功能减低的敏感度和特异度为95.00%、100%;整体LS均值-17.90%为界值,其敏感度和特异度与LS相同。结论应用超声STI技术可对LVNC患者左心室心肌功能进行深入定量评价。Objective To evaluate longitudinal left ventricular systolic function in patients with left ventricular noncompaction（LVNC） with speckle tracking imaging（STI）.Methods Twenty-one patients with LVNC and twenty-one age/sex-matched controls（control group） were enrolled.LVNC patients were divided into two groups： LVNC-1 group（LVEF≥50%,n=10） and LVNC-2 group（LVEF50%,n=11）.For STI,apex long-axis dynamic image of left ventricular were acquired.Curves and peak values of systolic longitudinal strain（LS） were obtained.Results Comparing with control group,LS of all level were significantly reduced（all P〈0.05）,LVEF,PWD E＇ and E/E＇ were significantly different in LVNC-2 group（all P〈0.05）.In contrast,LS reduced（all P〈0.05）,however,PWD E＇ and E/E＇ were not significantly different in LVNC-1 group.With an optimal cutoff value of LS was-20.71%,and the sensitivity and specificity was 95.00% and 100%,respectively.With an optimal cutoff value of globe LS was-17.90%,the sensitivity and specificity were the same as LS.Conclusion STI can quantitatively evaluate left ventricular function in the patients with LVNC.

关 键 词：孤立性心室肌致密化不全 斑点追踪显像 心肌收缩 

分 类 号：R541.1[医药卫生—心血管疾病] R540.45[医药卫生—内科学]