超声实时弹性成像整体应变率与局部应变率诊断乳腺病灶的比较  

Comparison on diagnostic value of entire strain ratio and localized strain ratio of real-time sonoelastography for differentiating breast solid lesions

作　　者：秦石成[1] 王俊玲[1] 崔可飞[1] 张瑞芳[1] 程安玲[1] 

机构地区：[1]郑州大学第一附属医院超声科,河南郑州450002

出　　处：《中国医学影像技术》2011年第5期963-966,共4页Chinese Journal of Medical Imaging Technology

摘　　要：目的比较超声实时弹性成像整体应变率(ESR)、局部应变率(LSR)对乳腺良恶性病灶的诊断价值。方法对113例患者共145个乳腺病灶(良性组:85个,恶性组:60个)分别行LSR、ESR两种应变率测量。以病理诊断为金标准,构建ROC曲线,分别获得两种方法鉴别乳腺病灶良恶性的最佳临界点,比较其诊断效率。结果构建ROC曲线后,ESR ROC曲线下面积(AUC)为0.90±0.03,最佳临界点为3.16,其敏感度、特异度、准确率分别为88.33%(53/60)、88.24%(75/85)、88.28%(128/145)。LSR的AUC为0.97±0.02,最佳临界点为31.15,其敏感度、特异度、准确率分别为96.67%(58/60)、94.12%(80/85)、95.17%(138/145)。LSR对乳腺病灶良恶性的诊断价值及准确率均优于ESR(P<0.05)。结论 ESR和LSR对乳腺病灶良恶性的鉴别诊断具有较大价值,LSR优于ESR。Objective To compare the diagnostic performance of entire strain ratio（ESR） and localized strain ratio（LSR） of real-time elasticity imaging for differentiating breast malignant and benign solid lesions.Methods One hundred and thirteen patients with 145 breast lesions（85 benign,60 malignant） were examined with the two strain ratio methods respectively.According to pathologic diagnosis,receiver operating characteristic（ROC） curves were used to explore the optimized cut-off points of them respectively and compare their diagnostic values.Results For ESR study,ROC curves revealed an area under the curve of 0.90±0.03,the optimized cut-off point of 3.16,and the sensitivity,specificity,accuracy was 88.33%（53/60）,88.24%（75/85）,88.28%（128/145） respectively,while those of LSR study was 0.97±0.02,31.15,96.67%（58/60）,94.12%（80/85）,95.17%（138/145）,respectively.The diagnostic performance and accuracy of LSR were better than those of ESR（P〈0.05）.Conclusion Both ESR and LSR are valid for differentiating breast solid lesions.LSR is superior to ESR method.

关 键 词：乳腺疾病 应变率 超声检查 弹性成像 ROC曲线 

分 类 号：R655.8[医药卫生—外科学] R445.1[医药卫生—临床医学]