高压氧治疗重度颅脑外伤远期疗效及相关因素分析  

Analysis of long term effect and influencing factors of hyperbaric oxygen on severe traumatic brain injury

作　　者：王泳[1] 刘洁[1] 李海东[1] 杨丽丽[1] 高亚利[1] 

机构地区：[1]首都医科大学附属复兴医院高压氧科,北京100038

出　　处：《中国康复医学杂志》2011年第5期411-414,共4页Chinese Journal of Rehabilitation Medicine

基　　金：北京市西城区卫生系统优秀人才培养专项经费资助项目(20080029)

摘　　要：目的:评价高压氧治疗重度颅脑外伤患者远期疗效并对其相关影响因素进行分析。方法:回顾性分析了2004年12月—2009年12月在我科进行高压氧治疗的44例重度颅脑外伤病例,远期疗效评定采用格拉斯哥结局量表(GOS)及残疾分级量表(DRS)。考虑的相关因素包括:高压氧开始治疗时间、高压氧治疗次数、入院时GCS(格拉斯哥昏迷量表)评分、损伤部位、有无气管切开、颅脑手术与否、基础疾病、神经系统并发症,以及其他系统并发症等,将上述因素对预后的影响进行统计学分析。结果:高压氧治疗后DRS评分明显下降(P<0.05),影响预后的主要因素包括:开始高压氧治疗时间、入院时GCS评分及神经系统并发症(P<0.05)。结论:高压氧治疗可以显著提高重度颅脑外伤患者的预后,高压氧治疗开始时间越晚、开始治疗前昏迷程度越深以及神经系统并发症越多,预后越差。Objective：To evaluate long term effect and influencing factors of hyperbaric oxygen （HBO） on patients with severe traumatic brain injury（TBI）. Method：Total 44 patients with severe TBI treated by HBO therapy from December 2004 to December 2009 were analyzed retrospectively. Main outcome measures contained the Glasgow outcome scale（GOS） and the disability rating scale （DRS）. The relative factors, including beginning time of HBO, times of HBO, Glasgow coma scale（GCS） scores at admission, locations of injury, incision of trachea, brain operation, previous diseases, neural complications and other complications, were investigated, the effectiveness of HBO on prognosis of severe TBI and the influences of relative factors were analyzed statistically. Result：The scores of DRS decreased significantly after HBO treatment （P0.05）. Beginning time of HBO, GCS score at admission and neural complications were major relative factors （P0.05）. Conclusion：HBO treatment can significantly enhance prognosis of patients with severe TBI. Delayed treament, severe coma and neural complications will induce poor prognosis.

关 键 词：高压氧 重度颅脑外伤 远期疗效 相关因素 

分 类 号：R473.72[医药卫生—护理学]