位移对双探头SPECT心肌显像质量的影响及校正  

Impact of Patient Motion on Myocardial Perfusion Imaging with Double-head SPECT and Assessment of Motion Correction

作　　者：戚忠智[1] 田蓉[1] 

机构地区：[1]四川大学华西医院核医学科,成都610041

出　　处：《四川大学学报（医学版）》2011年第3期392-396,共5页Journal of Sichuan University(Medical Sciences)

基　　金：Philips Medical System(项目编号:Exhibit C;CH22)资助

摘　　要：目的探讨体位移动对双探头单光子发射计算机化断层(SPECT)心肌显像图像质量的影响及校正方法。方法 20例患者在相同的采集条件下采用正常及主动移动进行门控采集,采用软件分别进行位移校正与非校正处理并进行位移分析,对心肌图像采用定量灌注SPECT(QPS)软件进行分节评分。结果缺损程度与位移幅度(r=0.58,P<0.01)、位移发生的频次(r=0.811,P<0.01)呈正相关。90%(18/20)的患者进行移动校正后图像质量有提高(P<0.05),校正后只有2.2%(7/318)的节段由原来的正常(评分0～1)变为非正常(评分2～4),而有35.3%(29/82)的节段由非正常评分变为正常评分。结论对于位移大于1个像素及1次以上移动的心肌显像患者应做移动校正。但对于位移大于3个像素以及频繁位移的患者校正效果不明显。Objective To investigate the impact of patient motion on myocardial perfusion imaging with double-head Single Photon Emission Computed Tomography（SPECT） and assess the effect of motion correction.Methods Twenty（20） patients were included in the study.Acquisitions were performed for all patients under the situations with or without body motion respectively.Images were reconstructed without or with motion correction software separately.The extent of perfusion defects was assessed by QPS（Quantitative Perfusion SPECT） with a 20-segment,5-point scoring system.Results The extent of artifacts and perfusion defects was related to the extent（r=0.58,P〈0.01） and frequency（r=0.811,P〈0.01） of patient motion.The image quality was improved in 18 of 20 patients（90%）significantly after motion correction（P〈0.05）.Only 2.2%（7/318） of segments that were previously considered normal（score=0 or 1） changed to abnormal（score=2-4） after motion correction,whereas 35.3%（29/82） of abnormal segments were reclassified as normal after motion correction.Conclusion Motion correction is necessary in myocardial perfusion imaging reconstruction if the range of patient motion is out of one pixel or the motion frequency is more than one time.But the correction is not helpful when the extent of body motion exceeds 3 pixel or the motion frequency is over one time.

关 键 词：位移 心肌显像 校正 SPECT 99m↑Tc-MIBI 

分 类 号：R541.4[医药卫生—心血管疾病]