城乡维吾尔族及汉族围产期妇女和新生儿巨细胞病毒IgM的检测分析  

Detection of CMV IgM by in Perinatal Women and Newborn Infants from Uygur and Han Nationalities and Correlation Analysis

作　　者：于中丽[1] 张彤[1] 

机构地区：[1]新疆医科大学微生物学教研室

出　　处：《地方病通报》1999年第3期26-28,共3页Endemic Diseases Bulletin

摘　　要：用生物学—亲和素酶联免疫吸附试验（ＡＢＣ－ＥＬＩＳＡ）法对维吾尔族及汉族围产期妇女（简称围产妇）和新生儿血清进行巨细胞病毒（ＣＭＶ）ＩｇＭ测定和关联分析。维吾尔族围产妇和新生儿感染率与汉族对应组存在显著差异（Ｐ＜０．０５），新生儿ＣＭＶ特异性抗体检出率与围产妇近期高感染率密切相关（Ｐ＜０．０５）。农村妊娠晚期妇女和新生儿ＣＭＶ的感染率均高于城市对照组（Ｐ＜０．０５）。研究结果提示：了解孕妇ＣＭＶ感染的动态变化和母子感染的内在联系，有助于指导围产妇的护理和降低婴儿的先天性感染。In this study,we have detected HCMV IgM in serum samples of perinatal women and newborn infants from Uygur and Han nationalities by ABC ELISA.The results showed that the positive rates of CMV IgM in perinatal women and newborn infants of two natinalities are significantly different (P<0.05),there was positive relation between perinatal women and newborn infants (P<0.05).The positive rates of CMV IgM in perinatal women and newborn infants from country side were higher than those from town (P< 0.05 ).By knowing the change of CMV infection in perinatal women and the internal relation of infection between mother and child,it should help to direct the antenatal care and diminish the congenital infection.

关 键 词：围产期妇女 新生儿 巨细胞病毒 ABC-ELISA 

分 类 号：R511[医药卫生—内科学] R446.62[医药卫生—临床医学]