距腓前韧带本体感受器分布研究  

Distributing of proprioceptor in human anterior talofibular ligament

作　　者：边海林[1] 徐向阳[1] 刘津浩[1] 朱渊[1] 王碧菠[1] 

机构地区：[1]上海交通大学附属瑞金医院骨科,200025

出　　处：《国际骨科学杂志》2011年第3期182-184,共3页International Journal of Orthopaedics

基　　金：国家自然科学基金(81071517)

摘　　要：目的测定距腓前韧带(ATFL)及周围组织的本体感受器数量及分布情况,由此推断本体感受器在踝关节运动中发挥的作用。方法选取10例新鲜尸体踝关节ATFL(年龄25～65岁,平均48.1岁),将韧带分为三段(近、中、远)许切成20μm厚的切片,采用免疫组织化学方法对标本进行染色并观察,将观察到的本体感受器进行分类和计数。结果 ATFL及周围组织均存在本体感受器,Ⅱ型和Ⅲ型本体感受器数量显著多于Ⅰ型本体感受器(P<0.001),韧带各部分间的本体感受器数量无明显差异(P>0.05)。结论 ATFL本体感受器以Ⅱ型和Ⅲ型小体为主,Ⅱ型和Ⅲ型本体感受器与运动觉和过度活动觉密切相关,其数量较多与踝关节维持稳定、避免关节活动讨度有关。Objective To determine the amount and distributing of proprioceptor in anterior talofibular ligament （ATFL） and periligamentous tissues. Thus the function of proprioceptor in ankle movement could be deduced. Methods ATFL from ten fresh cadaver ankle with ages ranging from 25 to 65 （mean 48. 1 ） years were collected. The ATFL were divided into three parts according to the bony attachments （proximal, central, and distal segments） before processing on serial sections of 20 μm thickness. The slices were stained by immunohistochemical method and examined under light microscopy. The proprioceptors were counted out and classified. Results The ATFL and periligamentous tissue were endowed with proprioceptors. There was a significant prevalence of proprioceptor type Ⅱ and type Ⅲ （P〈0. 001） compared with type I. However, there was no significant difference in the proprioceptors density in different part of ligament （P〉0. 05）. Conclusions The proprioceptor in ATFL and perillgamentous tissue are mostly composed by type Ⅱ and type Ⅲ. It have been confirmed that the proprioceptor type Ⅱ and type Ⅲ are correlate with sense of movement and protect the joint from excessive movement. The large density of proprioceptor type Ⅱ and type Ⅲ correlated with stability of ankle and avoid excessive movement of ankle.

关 键 词：距腓前韧带 本体感受器 免疫组织化学 

分 类 号：R684.7[医药卫生—骨科学]