极低出生体质量儿远期神经系统发育状况的研究  

Long-term neurodevelopmental outcomes of very low birth weight

作　　者：程琪(综述)[1] 王嘉俊(综述)[2] 富建华(审校)[1] 

机构地区：[1]中国医科大学附属盛京医院新生儿科,沈阳110004 [2]中国医科大学94期医学影像系,沈阳110001

出　　处：《国际儿科学杂志》2011年第3期223-225,共3页International Journal of Pediatrics

摘　　要：极低出生体质量儿（very low birth weight,VLBW）的出生率逐年增高,其存活率也随着NICU先进技术的发展日益上升,但VLBW的预后已成为社会关心的问题.近年来越来越多的研究证实,与足月儿相比,VLBW脑结构改变主要表现为脑容积、脑灰质容积和脑白质减少.因此,部分VLBW在儿童期出现了神经系统发育障碍等不良预后,可有认知障碍、行为和心理问题、运动笨拙等.The birth rate of very low birth weight（VLBW）is rising year by year,and its survival rate increases with developing of modern methods of neonatal intensive care.The outcomes of VLBW have become a social concern.VLBW have different brain structure compared with term children,mainly in the reduction of brain volume.including the reduction of gray matter volume and white matter vollame.Because of these pathologic changes in brain.some VLBW show severe neurodevelopmental disorders in childhood,including cognitive problems.behavioral and psychological problems,motor clumsiness and so on.

关 键 词：极低出生体质量儿 神经系统发育 

分 类 号：R722[医药卫生—儿科]