柯萨奇病毒与1型糖尿病发病关系研究进展  

Advancement of the relationship between coxsackie virus infection and type 1 diabetes

作　　者：陈思思(综述)[1] 郑禹(综述)[1] 李晓眠(审校)[1] 

机构地区：[1]天津医科大学微生物学教研室,300070

出　　处：《国际儿科学杂志》2011年第3期310-312,F0003,共4页International Journal of Pediatrics

摘　　要：近年来的研究表明,1型糖尿病（T1D）的发生与人类肠道病毒的感染关系密切,尤其是桐萨奇B组病毒.一方面,病毒感染可诱发T1D,且与病毒数量、病毒株型、宿主微环境等因素密切相关.另一方面,病毒感染也能抑制T1D的发生.该文从病毒感染诱发T1D的相关因素及病毒感染抑制T1D发生的可能机制这两方面探究柯萨奇B组病毒与T1D发病的关系.In recent years,the studies have shown that the incidence of type 1 diabetes（T1D）is closely related to the infection of human enteroviruses,particularly Coxsackie B Viruses（CVB）.On one hand.the researches show that vires infection can induce T1D,and it is associated with the viral amount.the viral strain,and the host microenvironment.On the other hand,the studies confirm that viral infection also can inhibit the incidence of T1D.In terms of the factors,which is related to the vires infection-inducing.T1D.and the possible mechanism of the virus infection-inhibiting-T1D,the article aims to explore the relationship between CVB infection and the incidence of T1D based on referring to foreign literatures in recent years.

关 键 词：柯萨奇B组病毒 1型糖尿病 

分 类 号：R587.1[医药卫生—内分泌]