三桥联杯[6]酰腙衍生物和相关化合物的合成  

Syntheses of Tri-bridging Calix[6]arene Hydrazone Derivative and Relative Compounds

作　　者：许冰婷[1] 杨发福[1,2] 刘志强[1] 柴先锋[1] 郭红玉[1] 

机构地区：[1]福建师范大学化学与材料学院,福州350007 [2]福建师范大学福建省高分子材料重点实验室,福州350007

出　　处：《有机化学》2011年第5期737-741,共5页Chinese Journal of Organic Chemistry

基　　金：国家自然科学基金(No.20402002);福建省自然科学基金(No.2009J01019);福建省高校杰出青年科研人才培育计划(No.JA10056)资助项目

摘　　要：以杯[6]芳烃和杯[6]-1,4-冠-4为起始原料,经过醚化引入酯基,接着用水合肼肼解得到杯[6]酰肼衍生物2和6,然后再与水杨醛进行缩合反应,高产率合成了两例杯[6]酰腙衍生物3和7.化合物6与2倍的二水杨醛乙二醚进行"1+2"缩合反应,得到了一例新型结构的杯[6]-1,4-2,6-3,5-三桥联酰腙衍生物8,产率73%.新化合物2,3,6,7和8的结构经元素分析、红外光谱、质谱、核磁共振谱等证实.Using calix[6]arene and calix[6]-1,4-crown-4 as starting materials,calix[6]arene hydrazide de-rivatives 2 and 6 were prepared by introducing ester groups with etherification and following hydrazinolysis reaction.Condensating 2 and 6 with salicylaldehyde gave two calix[6]arene hydrazone derivatives in high yields.By the ＂1＋2＂ condensation of compound 6 with 2 equiv.ethylene glycol disalicylaldehyde ether,a novel calix[6]-1,4-2,6-3,5-tri-bridging hydrazone derivative was synthesized in 73% yield.The structures of new compounds 2,3,6,7 and 8 were characterized by elemental analyses,IR,ESI-MS,1H NMR,etc.

关 键 词：杯[6]芳烃 三桥联 酰腙 合成 

分 类 号：O621.2[理学—有机化学]