益气血补肝肾中药对体外受精-胚胎移植临床结局的影响  

Effect of Herbal Medicines of Strengthening Qi and Blood Tonifying Liver and Kidney on Clinical Outcomes of IVF-ET

作　　者：邓伟民[1] 赵彦鹏[1,2] 葛明晓[1] 张金玉[1] 郭新宇[1] 

机构地区：[1]广州军区广州总医院,广东广州510010 [2]广州中医药大学

出　　处：《辽宁中医药大学学报》2011年第6期5-7,共3页Journal of Liaoning University of Traditional Chinese Medicine

基　　金：广东省中医药局科研课题(2009437)

摘　　要：目的:探讨辅助生育技术结合益气血补肝肾中药对体外受精-胚胎移植(IVF-ET)妊娠率的影响。方法:将行IVF-ET患者249例随机分成中药组(115例)及对照组(134例),两组均采用标准长方案垂体降调节治疗,中药组于促性腺激素释放激素激动剂(GnRH-a)降调节同时给予中药促黄体颗粒1周,给予促性腺激素(Gn)促排卵时加用经后增殖颗粒至HCG日;取卵后继续给予促黄体颗粒1周;对照组采用标准方案治疗不加用中药。对两组临床资料及结局进行分析。结果:两组患者HCG日E2、P、LH水平相比无显著性差异(P>0.05);中药组胚胎种植率及妊娠率高于对照组(P<0.05);中药组卵巢过度刺激综合征(OHSS)发生率低于对照组(P<0.05)。结论:在采取辅助生育技术的同时,运用益气血补肝肾中药能提高子宫内膜容受性,从而提高胚胎种植率和妊娠率。Objective：To observe the effect of herbal medicines of strengthening Qi and blood,tonifying liver and kidney on the gestation rate of IVF-ET.Methods：249 cases infertility patients were randomized into two groups,group A（n=115）and group B（n=134）.Two groups received routine regimen of IVF-ET.Additionally,group A received CuHuangti Granules from the day of medication of GnRH-a,received JinghouZengzhi from the day of medication of FSH to the day of administering HCG,and was given CuHuangti Granules from the day of embryo transfer.The datas of clinic and the clinic final were compared in the two groups.Results：The difference of serum E2,P,LH level were insignificant between the two groups on the day of administration of HCG（P〉0.05）.The implantation rate and gestation rate in group A was higher than that in group B（P〈0.05）.The morbidity of OHSS in group A was lower than that in group B（P〈0.05）.Conclusion：The application of herbal medicines of strengthening Qi and blood,tonifying liver and kidney can increase the implantation rate and gestation rate during assisted reproduction by increasing the endometrial receptivity.

关 键 词：益气血补肝肾 体外受精-胚胎移植 妊娠率 

分 类 号：R321.2[医药卫生—人体解剖和组织胚胎学]