国内耐药肺炎链球菌的流行现状  

Current status of drug resistance of Streptococcus pneumoniae in China

作　　者：姚开虎[1] 张敬仁[2] 

机构地区：[1]首都医科大学附属北京儿童医院儿研所微生物免疫室,100045 [2]清华大学医学院传染病研究中心,北京100084

出　　处：《传染病信息》2011年第2期120-124,共5页Infectious Disease Information

基　　金：国家自然科学基金(30801259)

摘　　要：肺炎链球菌可引起细菌性肺炎、中耳炎和脑膜炎等疾病,是当今发达国家和发展中国家共有的一个重要病原。由于抗生素长期的过度使用,许多肺炎链球菌菌株能够同时耐受多种常用的抗生素,使得临床可应用的有效抗生素越来越少。耐药肺炎链球菌正在朝着"超级细菌"方向发展。这种现状值得我们关注并寻求近期和长期的解决方法。本文对国内肺炎链球菌耐药现状及相关研究进行综述。Streptococcus pneumoniae is an important pathogen that causes devastating infectious diseases, such as bacterial pneumonia, otitis media and meningitis in both developed and developing countries. Due to the excessive use of antibiotics, the resistance of pneumococcal isolates to many of the commonly used antibiotics results in fewer effective antibiotics available for treat- ment. As the resistant S. pneumoniae is gradually approaching what the ＂superbug＂ is, the emergent situation demands our full attention and efforts in seeking short-and long-term solutions. This article provides an overview of the current status of drug resis- tance of S. pneumoniae and the related research in China.

关 键 词：肺炎链球菌 药物耐受性 抗菌药 

分 类 号：R378.14[医药卫生—病原生物学]