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作 者:李能平[1] 汤耀卿[2] 袁祖荣[2] 韩天权[2] 万志明[2] 张圣道[2]
机构地区:[1]上海市闸北区中心医院外科,200070 [2]上海第二医科大学附属瑞金医院外科,200025
出 处:《中国实用外科杂志》1999年第9期540-541,共2页Chinese Journal of Practical Surgery
摘 要:目的 探讨急性坏死性胰腺炎继发感染的早期诊断方法。方法 对13 例急性坏死性胰腺炎的临床、 C T 影像学、 C T 引导下细针穿刺( F N A) 结合 P C R 微生物学检查,诊断胰腺感染的敏感性、特异性进行前瞻性比较研究。结果 9 例最终诊断为胰腺感染,4 例为胰腺未感染。根据临床症状体征及常规实验室检查,诊断胰腺感染的敏感性为100 % (9/9) ,特异性为25 % (1/4) ; C T 气泡征诊断胰腺感染的敏感性为556 % (5/9) ,特异性为100 % (4/4) ; C T 引导下 F N A,抽吸物涂片诊断胰腺感染的敏感性为778 % (7/9) ,特异性为100 % (4/4) ,抽吸物 P C R 诊断胰腺感染的敏感性为889 % (8/9) ,特异性为100 % (4/4) 。结论 C T 引导下 F N A,抽吸物 P C R 诊断胰腺感染,有较高的特异性和敏感性,能适应临床快速诊断胰腺感染的要求。Objective To study the methods of early diagnosing pancreatic infection after acute necrotizing pancreatitis.Methods Compare the sensitivity and the specificity of clinical features,computed tomography scan,and CT-guided percutaneous fine needle aspiration(FNA)combined with PCR microbe identification prospectively in diagnosing pancreatic infection of 13 acute pancreatitis patients.Results 9 patients were diagnosed as pancreatic infection,4 patients non-pancreatic infection finally.The sensitivity and the specificity of clinical features to diagnose pancreatic infenction were 100%(9/9),25%(1/4)respectively,while extraluminal gas bubbles on CT scan were 55\^6%,100% respectively.By CT-guided percutaneous FNA,the sensitivity and the specificity of smear to diagnose pancreatic infection were 77\^8%(7/9),100% respectively,while PCR were 88\^9%(8/9),100% respectively.Conclusion The sensitivity and the specificity of FNA aspirates PCR to diagnose pancreatic infection are high,so PCR is suitable for early and rapid diagnosis of pancreatic infection.
分 类 号:R657.510.4[医药卫生—外科学]
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