用PCR检测尖锐湿疣患者的6,11型人乳头瘤病毒  

Use of Polymerase Chain Reaction For Detection of HPV-6,11 in Condyloma Acuminatum

作　　者：单可人[1] 何燕[1] 吕筠[2] 钟复光[1] 潘美兰[2] 徐德明[1] 王柄南 周茂梅 

机构地区：[1]贵阳医学院分子生物学研究室,贵阳550004 [2]贵阳医学院妇产科老专家门诊

出　　处：《贵阳医学院学报》1999年第3期229-230,233,共3页Journal of Guiyang Medical College

摘　　要：应用聚合酶链反应 (PCR)技术对 198例尖锐湿疣、疑尖锐湿疣患者进行HPV - 6 ,11感染的基因诊断。结果HPV - 6 ,11阳性 142例 ,阳性率 71 7% (142 / 198)。其中尖锐湿疣患者 10 6例 ,HPV - 6 ,11阳性 76例 ,阳性率 71 70 % (76 / 10 6 ) ;疑尖锐湿疣患者 92例 ,HPV - 6 ,11阳性 6 6例 ,阳性率 71 73% (6 6 / 92 )。说明无明显临床症状者 ,经PCR技术检测可得到诊断。Gene diagnosis with polymerase chain reaction was detected in 198 cases with condyloma acuminatum and doubtful condyloma acuminatum.HPV-6,11 DNA was demonstrated in 142 of 198(71 72%) among which HPV-6,11 DNA was 71 70%(76/106) for condyloma acuminatum and HPV-6,11 DNA was 71 73%(66/92) for doubtful condyloma acuminatum.So PCR technique for selective detecting HPV-6,11 DNA might be helpful to early finding and treatment of condyloma acuminatum and doubtful condyloma acuminatum then to prevent the marlignant changes of cervices.

关 键 词：乳头状瘤病毒 尖锐湿疣 聚合酶链反应 

分 类 号：R752.530.4[医药卫生—皮肤病学与性病学]