醋酸奥曲肽治疗恶性肠梗阻的疗效观察  

Therapeutic Observation of Octreotide in Treatment of Malignant Bowel Obstruction

作　　者：戴鹏[1] 

机构地区：[1]山西省肿瘤医院,山西太原030013

出　　处：《山西职工医学院学报》2011年第2期9-11,共3页Journal of Shanxi Medical College for Continuing Education

摘　　要：目的:探讨奥曲肽治疗恶性肠梗阻的疗效。方法:将48例无手术适应证的恶性肠梗阻患者随机分为25例奥曲肽组和23例对照组,两组均给予常规禁食、胃肠减压、补液及纠正水电解酸碱紊乱的治疗。奥曲肽组,在常规治疗基础上加用奥曲肽(力尔宁)0.2 mg,皮下注射,每6 h或8 h1次,连用3～14 d。结果:奥曲肽组的症状缓解率为80%,平均肛门排气时间为4.7 d,副反应发生率为12%;对照组症状缓解率为27%,平均肛门排气时间为7 d,副反应发生率为43.5%。结论:奥曲肽治疗恶性肠梗阻效果满意,且早期可逆转肠梗阻。Objective：To investigate the effect of octreotide in treatment of malignant bowel obstruction.Methods：Forty-eight patients with malignant bowel obstruction without surgical indication were randomly divided into an octreotide group（n=25） and a control group（n=23）.The two groups were treated with traditional treatment of fasting,gastrointestinal decompression,supplementing fluid and correcting water electrolysis balance.Based on the traditional treatment,the octreotide group was injected octreotide 0.2 mg hypodermically（once every 6 h or 8 h） for 3 to 14 days continually.Results：The symptom remission rate in the octreotide group was 80%,the average anal exhaust time was 4.7 days and the incidence of side effect was 12 %.The symptom remission rate in the control group was 27%,the average anal exhaust time was 7 days and the incidence of side effect was 43.5%.Conclusion：The effect of octreotide is content in treatment of malignant bowel obstruction and it could reverse bowel obstruction in the early stage of malignant bowel obstruction.

关 键 词：醋酸奥曲肽 恶性肠梗阻 治疗 

分 类 号：R725.3[医药卫生—儿科]