甘利欣治疗抗结核药物性肝功能损害的疗效分析  

CURATIVE EFFECT ANALYSIS OF GANLIXIN IN LIVER DYSFUNCTION CAUSED BY ANTI-TB DRUGS

作　　者：张涛[1] 何卫华[1] 周沛林[1] 佘冬梅[1] 卢全义[1] 

机构地区：[1]随州市疾病预防控制中心,随州441300

出　　处：《现代预防医学》2011年第11期2172-2173,2175,共3页Modern Preventive Medicine

摘　　要：[目的]探讨甘利欣治疗结核药性肝功能损害的临床疗效。[方法]将2007.1~2009.12月诊断为抗结核药物性肝炎86例住院病人进行随机分为治疗组及对照组,前者使用甘利欣治疗,后者进行常规性治疗,对其疗效进行分析。[结果]结核药物性肝炎多发生在抗结核治疗的强化期间,使用甘利欣治疗后其临床症状改善显著,治疗1周、2周、3周分别复查肝功能丙氨基酸转移酶（ALT）指标下降显著,治疗组疗效明显优于对照组。[结论]使用甘利欣治疗药物性肝炎,对临床症状改善及肝功能恢复情况均有明显效果,且廉价物美,临床用药安全,病人容易接受。[Objective]To investigate the effects of GanLiXin in liver dysfunction caused by Anti-TB drugs.[Methods]Randomly divided 86 patients who were diagnosed with anti-tuberculosis drug-induced hepatitis（from January 2007 to December 2009）into a treatment group and a control group：the former was treated with GanLiXin,the latter was treated with conventional treatment,and analyzed their effect.[Results]TB multi drug-induced hepatitis often occurred during anti-TB strengthened therapy,and the clinical symptoms were significantly improved after the use of GanLiXin.1 week,2 weeks,3 weeks after treatment,liver functions were reviewed,we found ALT were decreased significantly,the efficacy of the treatment group was significantly better than the control group.[Conclusion]The use of GanLiXin for the treatment of drug-induced hepatitis,not only can significantly improve the clinical symptoms but liver function also has a marked effect.At the same time,GanLiXin is inexpensive and safe clinical treatment,which is more receptive for patients.

关 键 词：结核病 肝炎 药物/疗法 甘利欣 

分 类 号：R969.4[医药卫生—药理学]