Ⅱ型糖尿病患者血脂水平在预防血管并发症上的临床意义  

THE CLINICAL SIGNIFICANCE ON THE CHANGES OF BLOOD LIPIDS IN PREVENTION OF VASCULAR COMPLICATIONS IN PATIENTS WITH DIABETES

作　　者：左惠芬[1] 李秀梅[2] 

机构地区：[1]邯郸市第一医院检验科,河北056002 [2]河北工程大学医学院检验系

出　　处：《现代预防医学》2011年第11期2174-2175,共2页Modern Preventive Medicine

摘　　要：[目的]探讨糖尿病患者血脂变化与血管并发症的关系。[方法]用日立型H7600型全自动生化分析仪检测符合WHO标准的糖尿病患者89例的血糖(GLU)、胆固醇(TC)、甘油三酯(TG)、高密度脂蛋白胆固醇(HDL-C)和低密度脂蛋白胆固醇(LDL-C)水平,并以正常人进行病例对照分析。[结果]糖尿病组较对照组CH、TG、LDL-C的含量显著升高(P﹤0.05),而HDL-C的含量较对照组显著降低(P﹤0.05);在糖尿病组中,有血管并发症较无血管并发症CH、TG、HDL-C的含量均明显升高(P﹤0.05);HDL-C含量显著降低(P﹤0.05)。[结论]糖尿病患者CH、TG、LDL-C升高,HDL-C降低,提示控制高血糖和高血脂有助于预防和延缓糖尿病血管病变的发生发展。[Objective]To investigate the relation between the changes in blood lipids and vascular complications in patients with diabetes.[Methods]Detected the levels of blood glucose（GLU）,cholesterol（TC）,triglyceride（TG）,high-density lipoprotein（HDL-C）and low-density lipoprotein（LDL-C）in 89 cases of diabetics who were in line with WHO standards with Hitachi model H7600-automatic biochemical analyzer,and carried out case-control analysis.[Results]The levels of CH,TG,LDL-C were significantly higher in the diabetic group than the control group（P﹤0.05）,while the levels of HDL-C were significantly lower than the control group（P﹤0.05）;In the diabetic group,the levels of CH,TG,LDL-C were significantly higher in vascular complications than those who were without vascular complications（P﹤0.05）;HDL-C contents were significantly lower（P﹤0.05）.[Conclusion]The levels of CH,TG,LDL-C elevate,HDL reduces in diabetics,suggesting that controlling high blood sugar and hyperlipemia can help to prevent and delay the occurrence and development of diabetic vascular disease.

关 键 词：糖尿病 血糖 血脂 血管并发症 

分 类 号：R587.1[医药卫生—内分泌]