中西药联合治疗慢性肾炎疗效观察  

Comparison of the curative effect of two treatment methods on patients with chronic nephritis

作　　者：郭乃火[1] 楚建元[1] 冉春风[1] 

机构地区：[1]深圳市龙岗中心医院社康科,广东省深圳518116

出　　处：《中国基层医药》2011年第10期1312-1314,共3页Chinese Journal of Primary Medicine and Pharmacy

摘　　要：目的 探讨中西医联合治疗慢性肾炎的疗效和不良反应.方法 100例慢性肾炎患者随机分为单纯西药组（对照组）50例和中西药结合组（治疗组）50例,观察各组疗效、尿常规、24 h尿蛋白定量、血浆白蛋白（Alb）、血肌酐（Scr）、尿素氮（BUN）等指标.结果 治疗组总有效率78.0%,明显高于对照组的52.0%（x2=3.841,P＜0.0,5）;三种分型之间疗效差异无统计学意义（x2=1.841,P＞0.0,5）;两组治疗后尿蛋白、BUN、Scr含量均低于治疗前（t=2.231、2.245、2.311,均P＜0.05）,Alb含量均高于治疗前（t=2.241,P＜0.05）;治疗后治疗组尿蛋白、BUN、Scr、Alb含量较对照组差异均有统计学意义（t=2.241、2.285、2.301、2.295,均P＜0.05）;治疗组不良反应2例（2.4%）,明显低于对照组的8例（16.0%）（x2=6.941,P＜0.01）.结论 中西药联合治疗慢性肾炎可延缓病情进展,可以取得较好的临床效果.Objective To study the curative effect and adverse reactions in patients with chronic nephritis by two treatment methods.Methods 1 00 cases with chronic nephritis were randomly divided into alone western medicine group（control group）50 cases and traditional Chinese combination western medicine group（treatment group）50cases,The index of efficacy,urinary protein of 24h,serum albumin（Alb）,serum creatinine（Scr）,blood urea nitrogen （BUN）were observed.Results The total effective rate 78.0%in treatment group was significantly higher than 52.0%in control group（x2=3.841,P＜0.05）;Three sub-types showed no significant efficacy difference（x2=1.841,P＞0.05）;The contents of urine protein,BUN,Scr levels after treatment were lower than before treatment in two groups（t=2.231,2.245,2.311,all P＜0.05）.The content of Alb after treatment was higher than before treatment（t=2.241,P＜0.05）;The contents of urinary protein,BUN,Scr,Alb after treatment were significantly different in two groups（t=2.241,2.285,2.301,2.295,all P＜0.05）;The adverse reactions in 2 cases（2.4%）in treatment group were significantly lower than 8 patients（16.0%）in control group（x2=6.941,P＜0.01）.Conclusion Traditional Chinese and western medicine could delay progression and obtain better clinical results in patients with chronic nephritis.

关 键 词：肾小球肾炎 慢性 中西医结合疗法 

分 类 号：R692[医药卫生—泌尿科学]