小麦纤维素治疗儿童功能性便秘的疗效观察  

Clinical trial of cellulose in treatment of functional constipation in children

作　　者：芦军萍[1] 黄瑛[1] 张烨[1] 王小卉[1] 邵彩虹[1] 

机构地区：[1]复旦大学附属儿科医院消化科,上海201102

出　　处：《中国当代儿科杂志》2011年第5期377-380,共4页Chinese Journal of Contemporary Pediatrics

摘　　要：目的研究小麦纤维素治疗儿童功能性便秘的有效性和安全性。方法采用前瞻性自身对照研究方法,对34例功能性便秘的患儿给予小麦纤维素治疗2周,观察治疗前后便秘症状及粪便性状改善情况,并进行量化评分比较。结果治疗后3 d、7 d和14 d,粪便性状、排便间隔、排便困难积分均明显下降;便秘症状总积分也明显下降,与治疗前比较差异有统计学意义(P<0.05)。治疗后3、7、14 d总有效率分别为37%、87%和90%。医生非常满意和比较满意率为57%,患儿家长非常满意和比较满意率为63%。服用小麦纤维素期间无不良反应发生。结论小麦纤维素治疗儿童功能性便秘疗效确切,安全性好。Objective To study the efficacy and safety of cellulose for the treatment of functional constipation in children. Methods A prospective, self-controlled, clinical trial using cellulose was conducted for 2 weeks in 34 children with functional constipation. The constipation symptoms and the characteristics of feces after the treatment were observed. Results The characteristics of feces and the constipation symptoms were improved significantly after the treatment. The total efficacy rate was 37% 3 days after treatment, 87% 7 days after treatment and 90% 14 days after treatment. The satisfactory rates of doctors and children＇s parents on the therapeutic effects were 57% and 63% , respectively. No adverse events, such as abdominal distention, pain or diarrhea, were observed during the treatment. Conclusions Cellulose is effective and safe in the treatment of functional constipation in children.

关 键 词：便秘 小麦纤维素 疗效 儿童 

分 类 号：R725.7[医药卫生—儿科]