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机构地区:[1]广州中医药大学,广东广州510006 [2]广州中医药大学第一附属医院,广东广州510006
出 处:《四川中医》2011年第5期26-28,共3页Journal of Sichuan of Traditional Chinese Medicine
摘 要:目的:对2型糖尿病患者瘀血舌象与PT、INR、APTT、FIB四项凝血指标之间的相关性进行探讨。方法:用Sysm ex CA1500全自动血凝分析仪检测136例2型糖尿病患者,77例正常人群体检者的凝血酶原时间(PT)、活化部分凝血酶时间(APTT)、国际标准化比值(INR)、纤维蛋白原(FIB)。结果:瘀血舌象组、非瘀血舌象组的PT均比正常组显著缩短(P<0.017,P<0.001);瘀血舌象组、非瘀血舌象组的APTT均比正常组显著缩短(P<0.001,P<0.017);非瘀血舌象组FIB水平显著高于正常组(P<0.017);瘀血舌象组FIB水平显著高于非瘀血舌象组(P<0.001)。结论:糖尿病患者体内凝血功能增强、纤溶功能升高,而糖尿病血瘀证患者体内凝血功能增强、纤溶功能升高可能是其出现瘀血舌象的病理基础之一。Objective: Probing in the correlation between tongue stasis pictures of diabetes and their four coagulation indicators such as PT,INR,APTT and FIB.Methods: By the Sysmex CA1500 automated blood coagulation analyzer,136 patients with type 2 diabetes and 77 healthy people were examined with the prothrombin time(PT),activated partial thromboplastin time(APTT),international normalized ratio(INR) and fibrinogen(FIB).Results: PT of congestion tongue group and non-congestion tongue group was significantly shorter than that of healthy people group(P〈0.017,P〈0.001).APTT of congestion tongue group and non-congestion tongue group was significantly shorter than taht of healthy people group(P〈0.001,P〈0.017).The level of FIB of non-congestion tongue group was higher than that of healthy people group(P〈0.017).The level of FIB of congestion tongue group was higher than that of non-congestion tongue group(P〈0.001).Conclusion: Coagulation and fibrinolysis is higher in diabetes,enhanced blood coagulation and fibrinolysis may be the pathological basis of tongue stasis pictures in diabetic patients with blood stasis.
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