MRSH耐消毒剂基因qacA/B/C、qacA的检测  

DETECTION ON qacA/B/C and qacA IN DISINFENTANT RESISTANT GENE OF MRSH

作　　者：秦淑国[1] 黄峰[1] 边其侠 蒲文君[1] 邵从军 许元元[1] 

机构地区：[1]皖北煤电集团总医院检验科,安徽宿州234000

出　　处：《中国消毒学杂志》2011年第3期324-326,I0001,共4页Chinese Journal of Disinfection

基　　金：安徽省淮北市科技局自然科学资金资助(080244)

摘　　要：目的了解安徽皖北地区临床分离的耐甲氧西林溶血葡萄球菌所携带的消毒剂基因状况。方法使用聚合酶链反应(PCR)方法检测45株MRSH中m ecA、qacA/B/C、qacA耐药基因。结果 45株临床分离的耐甲氧西林溶血性葡萄球菌均检出m ecA基因,检出率100%;qacA/B/C基因和qacA基因检出率分别为71.10%和64.44%。结论安徽皖北地区医疗机构分离出的耐甲氧西林溶血葡萄球菌qacA/B/C、qacA基因携带率高,潜在耐药倾向明显,应加强其耐药性监测。Objective To investigate the disinfectant resistant gene of meticillin resistant Staphylococcus Haemolyticus（MRSH） status in Anhui Wanbei area.Methods Polymerase chain reaction（PCR） was used to detect mecA,qacA/B/C and qacA resistance gene in 45 MRSH strains.Results Of 45 MRSH strains,mecA gene carrier rate was 100%,qacA/B/C and qacA gene carrier rate were 71.10% and 64.44% respectively.Conclusions qacA/B/C and qacA gene carry rate of MRSH was high in Anhui Wanbei area.Potential drug resistance is significantly.It should strengthen monitor the resistance.

关 键 词：耐甲氧西林溶血葡萄球菌 耐药基因 医院感染 监测 

分 类 号：R446.5[医药卫生—诊断学]