小剂量多巴酚丁胺负荷超声心动图识别冬眠心肌  

TWO-DIMENSTIONAL ECHOCARDIOGRAPHY WITH LOW DOSE DOBUTAMINE IN IDENTIFYING HIBERNATING MYOCARDIUM

作　　者：刘敏[1] 牛云枫[2] 李淑玲[3] 崔晓迎[4] 

机构地区：[1]内蒙古医学院附属医院内分泌科,内蒙古呼和浩特010050 [2]内蒙古医学院附属医院干部保健科 [3]内蒙古医学院附属医院超声影像科 [4]内蒙古医学院附属医院急诊科

出　　处：《内蒙古医学院学报》2011年第2期85-88,共4页Acta Academiae Medicinae Neimongol

基　　金：内蒙古医学院附属医院重大科研项目(NYFYZS2008003)

摘　　要：目的:评价小剂量多巴酚丁胺(dobutamine,DOB)负荷二维超声心动图(2-DE)实验识别冬眠心肌的准确性及安全性。方法:亚急性心肌梗死26例、陈旧性心肌梗死病人1例、不稳定型心绞痛3例、术前行小剂量DOB(5和10μg/kg.min),并成功进行了冠状动脉血运重建术(coronary revas-cularization,CRV),术后3mo左右进行了2-DE随访。用16节段半定量法分析各节段运动情况并给予分级记分。将该实验检出的冬眠心肌节段与CRV术后收缩功能改善的实际对比,评价本实验识别冬眠心肌的准确性、敏感性和特异性。结果:在186个异常节段中,小剂量DOB负荷2-DE实验检出29.6%和66.1%的冬眠心肌节段。结论:小剂量DOB负荷2-DE实验是识别冬眠心肌的准确、安全的方法。Objective：To evaluate the accuracy and safety of two-dimenstional echocardiography（2-DE） with low-dose dobutamin in identifying hibernating myocardium.Methods：2-DE with low-dose（5 and 10μg/kg·min）.DOB was done in 26 subacute myocardial infarction,1 old myocardial infarction and 3 unstable angina pectoris who were scheduled to undergo coronary revascularization（CRV）.CRV means successful and the follow up 2-DE was done about 3 month after CRV.By using a 16-segment model and semi-quantitative analysis method,the left ventricular regional wall motion and thickening in each segment was graded and scored.The hibernating myocardium segment detected were compared with the actual post-CRV functional improvement to evaluate the sensibility、specificity and accuracy of the test.Results：Among 186 abnormal segment,hibernating myocardium segments were detected by low-dose dobu tamin.2-DE test in 29.6% and 66.1%.Conclusion： 2-DE with low-dose dobutamine test was a acurate and safe method for identifying hibernating myocardium.

关 键 词：多巴酚丁胺 心肌梗死 超声心动图 

分 类 号：R274.9[医药卫生—中西医结合]