New wrestling rules of anti-inflammatory transrepression by oxysterol receptor LXR revealed  被引量:1

New wrestling rules of anti-inflammatory transrepression by oxysterol receptor LXR revealed

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作  者:Eckardt Treuter 

机构地区:[1]Centerfor Biosciences, Department of Biosciences and Nutrition, Karolinska Instituter, S-14183 Stockholm, Sweden

出  处:《Cell Research》2011年第5期711-714,共4页细胞研究(英文版)

摘  要:While nuclear receptors (NRs) generally function as transcriptional regulators of diverse metabolic, developmental and proliferative processes, some NRs also appear to modulate inflammatory processes such as those directed by Toll-like receptor (TLR) signaling in macrophages and other cell types of the innate immune system [1,2]. The medical and pharmaceutical interest in these pathways is

关 键 词:核受体 Toll样受体 显示 消炎 自然保护区 免疫系统 细胞信号 巨噬细胞 

分 类 号:Q71[生物学—分子生物学] Q257

 

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