Mice generated after round spermatid injection into haploid two-cell blastomeres  

作　　者：Hui Yang Linyu Shi Charlie Degui Chen Jinsong Li 

机构地区：[1]Laboratory of Molecular Cell Biology, Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, 320 Yueyang Road, Shanghai 200031, China [2]State Key Laboratory of Molecular Biology, Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, 320 Yueyang Road, Shanghai 200031, China [3]Shanghai Key Laboratory of Molecular Andrology, Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, 320 Yueyang Road, Shanghai 200031, China

出　　处：《Cell Research》2011年第5期854-857,共4页细胞研究（英文版）

基　　金：We thank Dr Xiang Gao of Nanjing University for providing EGFP-transgenic mice. We thank Drs Yixian Zheng of Carneige Institutation and Haifan Lin of Yale University for their critical and useful comments on the manuscript. This work was supported by grants from the Chinese Academy of Sciences （KSCX2-YW-R- 110, KSCX2-YW-R-229, XDA01010403）, the Ministry of Science and Technology （2007CB947101, 2009CB941101）, National Natural Science Foundation of China （30871430） and the Shanghai Municipal Commission for Science and Technology （07DZ22919, 08DJ1400502, 09PJ1410900）.

摘　　要：Dear Editor, It is well known that mature oocytes can reprogram somatic nuclei in the process of nuclear transfer （NT） [1] and remodel male gametes in normal fertilization. An intriguing question is whether blastomeres from cleavagestage embryos retain reprogramming activities. Recently,

关 键 词：卵裂球 精子细胞 单倍体 小鼠 注射 圆形 重新编程 体细胞核 

分 类 号：Q959.837[生物学—动物学] S814.8[农业科学—畜牧学]