A Mild and Highly Efficient Catalyst for Beckmann Rearrangement, BF3·OEt2  

作　　者：安娜 皮红军 刘力锋 杜文婷 邓卫平 

机构地区：[1]School of Pharmacy, East China University of Science and Technology, 130 Meilong Road, Shanghai 200237, China [2]Department of Pharmacy, Zhejiang Medical College, Hangzhou, Zhejiang 310053, China

出　　处：《Chinese Journal of Chemistry》2011年第5期947-950,共4页中国化学（英文版）

基　　金：Project supported by the National Natural Science Foundation of China （No. 20602011）, New Century Excellent Talents in University, the Ministry of Education, China （No. NCET-07-0283）, and ‘111＇ Project （No. B07023）.

摘　　要：BF3·OEte （Boron trifluoride etherate）, an inexpensive and commercially easily available Lewis acid stoichiometrically employed for Beckamann rearrangement in general, was now found to efficiently catalyze Beckmann rearrangement of ketoximes into their corresponding amides （up to 99% yield） in anhydrous acetonitrile under reflux temperature.BF3·OEte （Boron trifluoride etherate）, an inexpensive and commercially easily available Lewis acid stoichiometrically employed for Beckamann rearrangement in general, was now found to efficiently catalyze Beckmann rearrangement of ketoximes into their corresponding amides （up to 99% yield） in anhydrous acetonitrile under reflux temperature.

关 键 词：Beckrnann rearrangement BF3·OEt2 CATALYST AMIDE 

分 类 号：TQ225.261[化学工程—有机化工] TQ231.14