Mg(ClO4)2催化2-取代-4-甲酰基-1,2,3-三唑与β-环己二酮的缩合反应  

Condensation of 2-Substituted-4-formyl-1,2,3-triazole with β-Cyclohexanedione Catalyzed by Mg(ClO_4)_2

作　　者：刘晨江[1,2,3] 赵新海[2,3] 王昭申[2,3] 

机构地区：[1]新疆大学理化测试中心 [2]化学化工学院,石油天然气精细化工教育部＆自治区重点实验室 [3]乌鲁木齐绿色催化与合成技术重点实验室,乌鲁木齐830046

出　　处：《高等学校化学学报》2011年第6期1301-1304,共4页Chemical Journal of Chinese Universities

基　　金：国家自然科学基金(批准号:20662009,20862016);乌鲁木齐市科技计划项目(批准号:H101133001)资助

摘　　要：在Mg(C lO4)2催化下,2-取代-4-甲酰基-1,2,3-三唑代替传统的芳香醛与β-环己二酮在乙腈介质中进行缩合反应生成氧杂蒽,反应时间为5～6 h,产率75%～86%.该方法具有操作简便、反应时间短及产率高等优点,为此类化合物的合成提供了一种有效的新方法.在没有催化剂的体系中,反应生成的是氧杂蒽开环产物.The condensation reaction of 2-substituted-4-formyl-1,2,3-triazole instead of the ordinary aldehydes with β-cyclohexanedione was investigated by acrylonitrile as a reaction medium,employing Mg（ClO4）2 as the catalyst.It was found that when the reaction was carried out in the presence of Mg（ClO4）2,xanthenes was obtained.The reaction time was 5—6 h,and the yield ranged from 75% to 86%.This method has many advantages in the organic synthesis process,such as simple operation,short reaction time,and high yields,which afforded an effective method to synthesize the xanthenes.Further study show that this reaction could give xanthenediones ring-opening derivatives without additional catalyst.

关 键 词：氧杂蒽 Mg(ClO4)2 2-取代-4-甲酰基-1 2 3-三唑 

分 类 号：O621.25[理学—有机化学]