妇科门诊就诊者与收教所暗娼生殖道人乳头瘤病毒及其他性病感染情况调查  

The Current Infection Situation of Human Papilloma Virus(HPV) and Other Sexually Transmitted Disease(STD) among the Gynecology Clinic Clients and the Sex Workers in Reeducation Center in Tianjin

作　　者：郑钟洁[1] 程绍辉[1] 周宁[1] 潘玲 王欣[1] 郑敏娜[1] 

机构地区：[1]天津市疾病预防控制中心,300011 [2]现代女子医院

出　　处：《中国慢性病预防与控制》2011年第3期252-254,共3页Chinese Journal of Prevention and Control of Chronic Diseases

基　　金：天津市科技支撑计划重大项目(07SYSYSF05100)

摘　　要：目的了解人乳头瘤病毒(HPV)及其他性病在天津妇科门诊就诊者及收教所暗娼人群中的感染情况,以了解高危人群与妇科门诊就诊者HPV及其他性病感染差别。方法样本来源为天津市妇女收教所19～52岁卖淫女性86人,同时随机选择市区某医院妇科门诊18～59岁就诊者100例作为调查对象,在进行阴道镜检查的同时取宫颈处上皮细胞,用聚合酶链反应(PCR)方法采用HPV通用引物和HPV16/18特异性引物检测HPV病毒和高危型病毒亚型,同时做宫颈细胞病理检测,以验证实验结果与临床表现的符合情况。同时进行梅毒、淋病及沙眼衣原体感染等相关性传播疾病(STD)病原检测。结果妇科门诊就诊女性HPV病毒阳性率为9%,暗娼HPV病毒阳性率为32.2%。妇科门诊就诊者中检测出高危型HPV16型6例(占6%),HPV18型1例(占1%);暗娼中检出高危型HPV16型4例(占4.6%),HPV18型2例(占2.3%)。妇科门诊就诊者中梅毒螺旋体感染1例(占1%),淋病双球菌感染1例(占1%),沙眼衣原体感染2例(占2%);86例暗娼人群中梅毒螺旋体感染7例(占8.1%),淋病阳性7例(占8.1%),沙眼衣原体感染6例(占7.0%)。结论天津地区收教所暗娼和妇科门诊就诊者均检出HPV、梅毒、淋病及生殖道沙眼衣原体,但暗娼的感染率高于妇科门诊就诊者。Objective To investigate the infection situation of Human papilloma virus （HPV） and other sexually transmitted disease （STD） among the gynecology clinic clients and the sex workers in reeducation center in Tianjin. Methods 86 of sex workers aged 19-52 years old were selected from the reeducation center in Tianjin and 100 of gynecology clinic clients aged 18~ 59 years old were randomly selected from the Gynecology clinic of a hospital in Tianjin. All of them were taken colposcopy examination while obtained of their cervical epithelial cells. We used universal primers and HPV 16/18 specific primers to identify the genotype by PCR. Meanwhile, cervical cells pathology tests was done to verify the consistency of PCR results with the clinical manifestations. The pathogen detections of syphilis, gonorrhea and chlamydia trachomatis were also examined. Results The positive rate of HPV infection in the gynecology clinic clients was 9%, and the rate in sex workers in reeducation center was 32.2%. There were 6 cases with HPV16 （6%） and 1 with HPV18 （1%） in the gynecology clinic clients, while 4 cases with HPV16 （4.6%） and 2 with HPV18 （2.3%） in sex workers in reeducation center. There were 1 case of syphilis （1%）, 1 of gonorrhea （1%） and 2 of chlamydia trachomatis （2%） in the gynecology clinic clients, while 7 cases of syphilis （8.1%）, 7 of gonorrhea （8.1%） and 6 of chlamydia trachomatis （7.0%） in sex workers in reeducation center. Conclusion HPV was detected both in the gynecology clinic clients and the sex workers in reeducation center in Tianjin, and the rates of HPV infection, as well as syphilis, gonorrhea and chlamydia trachomatis infections in sex workers in reeducation center were higher than those in the gynecology clinic clients.

关 键 词：人乳头瘤病毒 性传播疾病 病毒性 病毒基因分型 

分 类 号：R759[医药卫生—皮肤病学与性病学]