胸廓外持续负压对健康犬血流动力学及呼吸力学的影响  

Effects of Continuous Negative Extrathoracic Pressure on Hemodynamics and Pulmonary Mechanics in Dogs

作　　者：李燕芹[1] 钮善福[1] 朱蕾[1] 郑玉龙[2] 宋元林[1] 白春学[1] 

机构地区：[1]上海医科大学中山医院呼吸病研究所,上海200032 [2]江苏省淮阴市第二人民医院呼吸科,淮阴223000

出　　处：《上海医科大学学报》1999年第5期353-355,共3页Journal of Fudan University(Medical Science)

基　　金：卫生部直属医疗机构临床学科重点项目基金!资助(CD96/ 2 6)

摘　　要：目的　比较胸廓外持续负压(CNEP)和呼气末正压(PEEP)对健康犬血流动力学和呼吸力学的影响。方法　通过实验犬股静脉插入SwanGanz漂浮导管,监测不同通气状态下血流动力学,并记录呼吸力学指标。结果　CNEP与PEEP比较,前者对血流动力学和呼吸力学指标均无明显影响,同时对尿量也无影响。而PEEP不仅影响血流动力学和呼吸力学指标,还使尿量明显减少。结论　CNEP联合间歇正压通气(IPPV)不会对血流动力学和呼吸力学产生不利影响,因此在某些病理状态下可考虑选择CNEP。To compare the hemodynamics and pulmonary mechanics effects of CNEP and PEEP. Methods A Swan Ganz catheter was inserted through femoral vein in order to measure hemodynamics parameters.At the same time,pulmonary mechanics parameters were recorded. Results CNEP had no influence on the hemodynamics,pulmonary mechanics and urinary output.But PEEP not only affected hemodynamics and pulmonary mechanics,but also resulted in decrease in urinary output. Results CNEP had no influence on the hemodynamics,pulmonary mechanics and urinary output.But PEEP not only affected hemodynamics and pulmonary mechanics,but also resulted in decrease in urinary output. Conclusions The results suggested that IPPV with CNEP had not bad effect on hemodynamics and pulmonary mechanics.So CNEP may be considered as an alternative for patients in whom an unstable hemodynamics status exists.

关 键 词：胸廓外持续负压 血流动力学 呼吸力学 PEEP 

分 类 号：R459.6[医药卫生—治疗学] R332.1[医药卫生—临床医学]