正常人股骨颈骨密度变化(附425例双能X线骨密度仪测量分析)  

Bone Mineral Analysis of Femoral Neck in 425 Normal Subject by Measurement ofDual Energy X-ray Absorptiometry

作　　者：张东[1] 姚安晋[1] 刘陈学[1] 阎富梅[1] 余建国[1] 张震[1] 

机构地区：[1]西安市红十字会医院影像科,710054

出　　处：《实用放射学杂志》1999年第11期676-676,共1页Journal of Practical Radiology

摘　　要：目的：了解正常人股骨近端各部位骨密度变化，以确定骨密度值的正常范围，为临床预防、诊断、治疗骨质疏松奠定基础。方法：采用双能Ｘ线骨密度仪测量４２５例正常自愿者股骨近端各部位骨密度值，男性２２２例，平均年龄４９．５７岁，女性２０３ 例，平均年龄４４．４２岁，按１０岁一个年龄组统计分析。结果：男性各部位骨峰值均分布在２０～２９岁年龄组；女性Ｌ－ Ｎｅｃｋ、Ｔｒｏｃｈ 峰值出现较晚，分布在３０～３９岁年龄组；Ｒ－ Ｎｅｃｋ、Ｗａｒｄ＇ｓ区骨峰值分布在２０～２９ 岁年龄组。男、女两性同部位之间骨密度峰值比较表明，男性股骨颈和大粗隆的值均高于女性，统计学分析有非常显著性差异（Ｐ＜ ０．０１），同性别股骨近端双侧对照统计学结果没有显著性差异（Ｐ＞ ０．０５）。男性６０～６９岁年龄组骨密度有上升趋势。本组各部位骨峰值明显低于国内类似研究（不同机型、不同地区）的结果（Ｐ＜ ０．０１）。结论：提供了正常人各年龄组股骨近端各部位骨密度变化特点，对国人骨矿物密度正常值有重要的参考价值。为骨质疏松的研究积累了数据和资料。Objective:To understand the changes of bone mineral density(BMD) and to build normal value of femoral neck in normal subjects as the basis for prevention,diagnosis and treatment of osteoporosis.Methods:BMD was measured by Dual energy X-ray absorptiometry(DEXA)at three sites(neck,greater trochanter,Ward's triangle)of the proximal femur in 425 normal volunteers.There were 222 males(mean age 49.57 years)and 203 females (mean age 44.42 years).They were divided into groups according for analysis.Results:In males the peak of bone density was in the group of 10～29 years.In females,the peak of bone density of the left-neck(L-Neck),left-greater trochanter(L-Troch)and right-greater trochanter(R-Torch) was in 30～39 years age-group;while the peak of bone density of R-Neck and Ward's region was in 20～29 years age-group.The comparson of the peck of bone density in the same region of femur between malse and females showed that the peck of bone density of neck and great trochanter was higher in males than that in females(P<0.01).Bone density was not significantly different between both sides of femora in the same sex(P>0.05).there was a tendency of increased MBD among the 60～69 years age-group.The peak of bone density of each region of femur in this study was significantiy lower compared with other data of internal study(P<0.01),differant machine and area (P<0.01).Conclusion:This sutdy shows the normal range and characteristics of BMD of the proximal femur for both males and females in Chinese.It has important reference value will be helpful for reseach of osteoporosis.

关 键 词：骨质疏松 骨密度 X线 诊断 股骨 颈骨 

分 类 号：R681.04[医药卫生—骨科学] R816.8[医药卫生—外科学]