多重线性回归分析及优选义齿粘附剂配方  

Optimization of denture adhesive's formula by multiple linear regression and orthogonal design methods

作　　者：余穗华 袁贤君 赵克[3] 

机构地区：[1]广州市越秀区口腔医院,医师广东510100 [2]广州市开发区医院口腔科,主治医师广东510730 [3]中山大学光华口腔医学院.附属口腔医院修复科,主任医师广东510055

出　　处：《中华老年口腔医学杂志》2011年第1期39-42,共4页Chinese Journal of Geriatric Dentistry

基　　金：广东省科技计划项目(编号:2010B060900045)

摘　　要：目的:优选Comfort-DA II型义齿粘附剂配方。方法:以粘结抗张强度值为评价标准,联用多重线性回归分析及正交设计法确定Comfort-DA II型义齿粘附剂的最佳配比。结果:聚氧化乙烯0.3125g、甲基纤维素1.250g、海藻酸钠0.5625g、羟乙基纤维素0.154g时,义齿粘附剂的粘结抗张强度值最高。结论:联用多重线性回归分析及正交设计法可有效地确定Comfort-DA II型义齿粘附剂的最佳配比。Objective： Optimization of Comfort-DA II＇ s formula. Methods： Each factor of affecting tensile bond strength of Comfort-DA II was analyzed to select the best formula by combining multiple linear regression and orthogonal design. Results： When polyethylene oxide is 0.3125g, methyl cellulose is 1.250g, sodium alginate is 0.5625g, and hydroxyethyl cellulose is 0.154g, tensile bond strength of Comfort-DA II is at the best condition. Conclusion： The combination of multiple linear regression and orthogonal design is an effective methodology in the optimization of Comfort-DA II＇s formula.

关 键 词：多重线性回归分析法 正交设计法 义齿粘附剂 配方 

分 类 号：R783[医药卫生—口腔医学]