核桃楸树皮提取物对志贺氏菌抑菌效果研究  

Antibacterial Effect of Extract from Bark of Juglans Mandshurica on Shigella

作　　者：黄余龙[1] 饶燕[1] 黄山[1] 黄妙婵[1] 

机构地区：[1]东莞市人民医院药剂科,广东东莞523018

出　　处：《现代生物医学进展》2011年第10期1921-1923,共3页Progress in Modern Biomedicine

摘　　要：目的:观察核桃楸树皮提取物对志贺氏菌的抑菌效果。方法:采用两倍稀释法和纸片琼脂扩散法考察桃楸树皮提取物对志贺氏菌的抑菌作用。结果:核桃楸树皮提取物对痢疾志贺氏Ⅰ型菌、痢疾志贺氏Ⅱ型菌、鲍氏志贺Ⅰ型菌、宋内氏志贺菌均为0.0313g/mL,福氏志贺Ⅱ型菌为0.0625g/mL。结论:核桃楸树皮提取物对志贺氏菌均有良好的抑菌作用,各菌对药物的敏感强弱顺序为:宋内氏志贺菌>鲍氏志贺Ⅰ型菌>痢疾志贺Ⅰ型菌>痢疾志贺菌Ⅱ型菌>福氏志贺Ⅱ型菌。Observation the antibacterial of Shigella by the juglans mandshurica maxim bark extraction. Methods： Using double dilution and disc agar diffusion method to study inhibition of Shigella bacteria in juglans mandshurica maxim bark extraction. Results： MIC of the juglans mandshurica maxim bark extraction on Shigella dysenteriae type Ⅰ strain,Shigella dysenteriae type Ⅱ strain , Shigella boydii type I and Shigella sonnei strain are 0.0313g/mL, Shigella bacteria type Ⅱ strain is 0.0625g/mL type. Conclusion： The juglans mandshurica maxim bark extraction have good antimicrobial effect on Shigella, The order of drug-sensitive strains of the strength ： Shigella sonnei strain 〉 Shigella boydii type Ⅰ strain〉 Shigella dysenteriae type I strain〉 Shigella dysenteriae type II strain 〉 Shigella bacteria type II strain.

关 键 词：核桃楸树皮 志贺氏菌 最低抑菌浓度(MIC) 

分 类 号：R285.5[医药卫生—中药学] R378.25[医药卫生—中医学]