志贺菌多耐药现状与多耐药机制  

Multi-drug Resistance Current Situation and Mechanisms of Shigella spp.

作　　者：穆瑞瑞[1] 蔺芳[1] 陈泽章[2] 段广才[3] 吴健[4] 

机构地区：[1]新乡学院生命科学与技术系,河南新乡453000 [2]新乡学院物理系,河南新乡453000 [3]郑州大学公共卫生学院,郑州450001 [4]郑州大学生物工程系,郑州450001

出　　处：《中国农学通报》2011年第12期266-270,共5页Chinese Agricultural Science Bulletin

基　　金：河南省科技攻关项目资助课题"志贺菌耐药分子基础研究"(0424410035)

摘　　要：志贺菌属细菌是引起细菌性痢疾(菌痢)的主要病原菌。近年来,随着抗菌药物大量用于治疗菌痢,临床上出现大量多重耐药志贺菌株,这些多耐药株产生速度快,耐药率高,从而使菌痢的发病率居高不下。为了控制菌痢的蔓延及流行,研究志贺菌属的多重耐药机制迫在眉睫。为了详细了解志贺菌属细菌的多重耐药机制及探索解决其问题的途径,本研究旨在对志贺菌属细菌的耐药机制做一综述。Shigella is the main pathogen of shigellosis.Since antimicrobial agents were generous employed to treat shigellosis in recent years,clinical multiple-antibiotic-resistance in Shigella spp.had been widely appeared,which had a quickly speed and a high antibiotic-resistance rate.So it had a high incidence rate.In order to control the spread and prevail of shigellosis,it was imminent to study the multiple-antibiotic-resistant mechanisms in Shigella spp..In order to know the multiple-antibiotic-resistant mechanisms in clinical strains of Shigella spp.in full and quest for the track to solve problem,the purpose of this article was to summarize the mechanism of resistant of Shigella spp.

关 键 词：志贺菌属 多重耐药 耐药机制 

分 类 号：Q939.93[生物学—微生物学]