血氟测定的比较研究  

A comparative study on blood fluoride determination methods

作　　者：刘克俭[1] 郑红燕[1] 刘芸[1] 陈荣安[1] 

机构地区：[1]同济医科大学职业医学研究所,武汉市430030

出　　处：《中国职业医学》1999年第4期4-5,共2页China Occupational Medicine

基　　金：国家"九五"攻关项目资助

摘　　要：目的　为使血氟测定简便化，探讨末梢血氟代替静脉血氟及血清氟的可能性。方法　随机选取研究对象２７ 人，分为氟组和对照组。氟组给予含氟１０ ｍｇ／Ｌ的茶水３００ ｍｌ 饮用。利用“微量加标对电极法”测定１ 小时后新鲜血样及放置４ ℃４８ 小时后的末梢血、静脉血及血清氟含量。结果　各组存放前的末梢血与静脉血、末梢血与血清的氟含量具有相关性（ｒ 为０ ．３６４ 和０ ．５８２） ，存放后末梢血氟与静脉血氟一致，且较存放前明显升高。结论　存放前末梢血氟可反映血中的氟含量。Objective To simplify the fluoride determination method. Methods 27 volunteers were randomly selected and divided into 2 groups, the fluoride group and the control group. 300 ml boiled water (containing sodium fluoride 10 mg/L) was drank by the fluoride group. The F - concentration in peripheral blood (from finger tip), venous blood and serum were determined right after drinking for 1 h and after storing at 4℃ for 48 h. Results The results showed that the concentration of F - in peripheral blood appeared to be correlated with that in venous blood and in serum ( r =0.36, r =0.58) before storing. After 48 h storing, the F - in peripheral blood had no difference with that in venous blood. Conclusion It suggested that the F - in pre storing peripheral blood could represent the level of F - in venous blood.

关 键 词：氟化物 测定方法 比较研究 血氟 氟病 

分 类 号：R446.112[医药卫生—诊断学]