炮制对藏药南寒水石钙溶出率的影响  

Impact of Processing on Dissolution Rate of Calcium of Traditional Tibetan Medicine Nanhanshuishi

作　　者：全正香[1,2,3] 杜玉枝[1,2] 魏立新[1,2] 肖远灿[1,2] 杨红霞[1,2,3] 李岑[1,2,3] 

机构地区：[1]中国科学院西北高原生物研究所,西宁810008 [2]青海省藏药药理学与安全性评价研究重点实验室,西宁810008 [3]中国科学院研究生院,北京100039

出　　处：《中国实验方剂学杂志》2011年第11期16-18,共3页Chinese Journal of Experimental Traditional Medical Formulae

基　　金："重大新药创制"科技重大专项(2009ZX09308-003)

摘　　要：目的:通过测定各产地藏药南寒水石不同炮制品钙溶出率,揭示炮制对南寒水石钙溶出率的影响。方法:运用EDTA滴定法测定青海、西藏、甘肃、四川四省区产地藏药南寒水石生品、水淬品、酒淬品、酸酪淬品水煎液钙溶出率。结果:各种炮制方法均能显著提高藏药南寒水石水煎液钙溶出率,除黄南浪加和甘南合作美其乡的样品外,其余各产地南寒水石炮制品水煎液钙溶出率大小顺序均为酸酪淬品>酒淬品>水淬品。结论:通过测定和比较各产地藏药南寒水石不同炮制品的钙溶出率,为评价各产地南寒水石的品质、阐明南寒水石炮制机理和规范其炮制工艺提供了基础数据。Objective：To reveal the impact of process on dissolution rate of calcium of traditional Tibetan medicine Nanhanshuishi by determining various processed Nanhanshuishi decoctions.Method：The calcium content in various Nanhanshuishi（crude,water quenched,liquor quenched,and yoghurt quenched） was determined by EDTA titration.Result：The dissolution rate of calcium of traditional Tibetan medicine Nanhanshuishi was raised after being processed,the order of dissolution rate of calcium of processed Nanhanshuishi was the yoghurt quenchedthe liquor quenchedthe water quenched.Conclusion：The study has provided basis for evaluating quality,clarifying the processing mechanism and regulating the processing technology of traditional Tibetan medicine Nanhanshuishi.

关 键 词：矿物药 南寒水石 溶出率 钙 炮制 

分 类 号：R283.4[医药卫生—中药学]